| .CDF | Wolfram Research | 頁面佈局檔案 | Computable Document Format File | Wolfram Research CDF Player | Wolfram Research |
| .FITS | Open Source | 光柵圖像檔案 | Flexible Image Transport System File | Wolfram Research Mathematica | Wolfram Research |
| .M | MathWorks | 開發商檔案 | MATLAB Source Code File | Wolfram Research Mathematica | Wolfram Research |
| .MA | Autodesk, Inc. | 三維圖像檔案 | Maya Project File | Wolfram Research Mathematica | Wolfram Research |
| .MDB | Microsoft Corporation | 資料庫檔案 | Microsoft Access Database | Wolfram Research Mathematica | Wolfram Research |
| .MM | Kodak | 資料檔案 | Kodak EasyShare Thumbnail Cache File | Wolfram Research Mathematica | Wolfram Research |
| .MX | Wolfram Research | 資料檔案 | Mathematica Serialized Package File | Wolfram Research Mathematica | Wolfram Research |
| .NB | Wolfram Research | 試算表檔案 | Mathematica Notebook | Wolfram Research Mathematica | Wolfram Research |
| .NBP | Wolfram Research | 資料檔案 | Mathematica Player Notebook File | Wolfram Research Mathematica | Wolfram Research |
| .PIXAR | Pixar | 光柵圖像檔案 | Pixar Image File | Wolfram Research Mathematica | Wolfram Research |
| .PLY | MakeMusic, Inc. | 音頻檔案 | Finale Playback File | Wolfram Research Mathematica | Wolfram Research |
| .PNM | XnSoft | 光柵圖像檔案 | Portable Any Map Image | Wolfram Research Mathematica | Wolfram Research |
| .PXR | Pixar | 光柵圖像檔案 | Pixar Image File | Wolfram Research Mathematica | Wolfram Research |
| .TGF | Unknown Developer | 資料檔案 | Trivial Graph Format File | Wolfram Research Mathematica | Wolfram Research |
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