| .E00 | ESRI | GIS檔案 | ArcInfo Coverage Export File | ESRI ArcGIS for Desktop | ESRI (Environmental Systems Research Institute) |
| .EAZ | ESRI (Environmental Systems Research Institute) | 資料檔案 | ArcGIS Explorer Add-in File | ESRI ArcGIS for Desktop | ESRI (Environmental Systems Research Institute) |
| .ECW | ESRI (Environmental Systems Research Institute) | 光柵圖像檔案 | Enhanced Compression Wavelet Image | ESRI ArcGIS for Desktop | ESRI (Environmental Systems Research Institute) |
| .EFS | ESRI | GIS檔案 | ESRI Spatial Binary File | ESRI ArcGIS for Desktop | ESRI (Environmental Systems Research Institute) |
| .EGD | ESRI (Environmental Systems Research Institute) | GIS檔案 | Encrypted Grid Shape File | ESRI ArcGIS for Desktop | ESRI (Environmental Systems Research Institute) |
| .ERS | ESRI (Environmental Systems Research Institute) | GIS檔案 | ER Mapper Data File | ESRI ArcGIS for Desktop | ESRI (Environmental Systems Research Institute) |
| .ESI | Open Source | 遊戲檔案 | Escape Level Index File | ESRI ArcGIS for Desktop | ESRI (Environmental Systems Research Institute) |
| .ETA | Google | GIS檔案 | Google Earth Placemark File | ESRI ArcGIS for Desktop | ESRI (Environmental Systems Research Institute) |
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