| .TSTREAM | Open Source | Arquivos miscelâneas | SwarmPlayer Streaming Torrent | SwarmPlayer | Open Source |
| .TTA | True Audio | Arquivos de áudio | True Audio File | XMMS | Open Source |
| .TTC | Various Developers | Arquivos de fonte | TrueType Font Collection | FontForge | Open Source |
| .TTF | Apple | Arquivos de fonte | TrueType Font | FontForge | Open Source |
| .TTL | Unknown Developer | Arquivos de jogos | AGT Game Title File | AGiliTy | Open Source |
| .TTS | SumTotal Systems | Arquivos de dados | ToolBook Translation System File | Media Player Classic | Open Source |
| .TUN | High Voltage Software | Arquivos de áudio | LEGO Racers Audio File | Audacity | Open Source |
| .TWL | Open Source | Arquivos GIS | Naviguide Binary GPS Track Data File | GPSBabel | Open Source |
| .TX8 | Microsoft Corporation | Arquivos de Texto | DOS Text File | PSPad | Open Source |
| .TXL | Open Source | Arquivos de desenvolvedor | TXL Source Code | PSPad | Open Source |
| .TXS | Delphi Softwares | Arquivos miscelâneas | Beast (Trojan Horse) Data File | Tiny XML Server | Open Source |
| .TXTZ | Open Source | Arquivos eBook | Compressed eBook File | Calibre | Open Source |
| .TXX | National Library of Medicine | Arquivos de desenvolvedor | Insight Segmentation And Registration Toolkit Data File | Insight Segmentation and Registration Toolkit | Open Source |
| .TXZ | Open Source | Arquivos comprimidos | XZ Compressed Tar Archive | Tukaani XZ Utils | Open Source |
| .TZX | Kromasoft | Arquivos de jogos | Tanzzle Graphic Object File | Fuse | Open Source |
| .U | Epic Games | Arquivos de jogos | Unreal Tournament Class Package | Dragon UnPACKer | Open Source |
| .UAX | Epic Games | Arquivos de áudio | Unreal Audio Package | Dragon UnPACKer | Open Source |
| .UB | Waveform Software | Arquivos de áudio | Unsigned Byte Audio File | SoX | Open Source |
| .UBIFS | Various Developers | Arquivos de imagem de disco | Linux UBIFS Image | Linux | Open Source |
| .UBJ | The Buzz Media | Arquivos de dados | Universal Binary JSON File | Ubjson.NET | Open Source |
| .UDF | Open Source | Arquivos de imagem de disco | Universal Disk Format Image File | PeaZip | Open Source |
| .UKX | Epic Games | Arquivos de jogos | Unreal Animation Package | Dragon UnPACKer | Open Source |
| .ULT | Radionomy | Arquivos de áudio | UltraTracker Module | CocoModX | Open Source |
| .UMF | GetMediaHolder.com | Arquivos de dados | MediaHolder Universal Media Format File | PSPad | Open Source |
| .UMS | Open Source | Arquivos comprimidos | Dragon UnPACKer Version 5 Archive File | Dragon UnPACKer | Open Source |
| .UMX | Epic Games | Arquivos de jogos | Unreal Music Package | ModPlug Player | Open Source |
| .UNF | Open Source | Arquivos de jogos | UNIF ROM File | Nestopia | Open Source |
| .UNI | Open Source | Arquivos de áudio | MikMod UniMOD Module | CocoModX | Open Source |
| .UPD | Various Developers | Arquivos de Texto | Program Update Information | Notepad2 | Open Source |
| .UPR | Open Source | Arquivos de dados | Fractal Parameters File | Apophysis | Open Source |
| .UPS | Open Source | Arquivos de jogos | UPS Patch File | MultiPatch patching tool | Open Source |
| .UPT | Open Source | Arquivos de dados | Connectivity Memory Model Update Timing Input Data File | Neural Network Simulation Software | Open Source |
| .UPX | Open Source | Arquivos comprimidos | Ultimate Packer For eXecutables File | PeaZip | Open Source |
| .USR | FileMaker Inc. | Arquivos de banco de dados | FileMaker Pro Database File | GPSBabel | Open Source |
| .USX | Epic Games | Arquivos de jogos | Unreal Static Meshes | Dragon UnPACKer | Open Source |
| .UTX | Epic Games | Arquivos de jogos | Unreal Texture Package | Dragon UnPACKer | Open Source |
| .UTXT | Open Source | Arquivos de Texto | Unicode Text File | Notepad2 | Open Source |
| .UU | Open Source | Arquivos codificados | Uuencoded File | Uuencode | Open Source |
| .UUD | Open Source | Arquivos codificados | UUDecoded File | UUDeview | Open Source |
| .UUE | Open Source | Arquivos codificados | Uuencoded File | Uuencode | Open Source |
| .UWF | Marc Andrй Schallehn | Arquivos de áudio | UltraTracker Wave File | CocoModX | Open Source |
| .V | Microsoft Corporation | Arquivos de imagem Raster | Subsampled Raw YUV Image | Icarus Verilog | Open Source |
| .V3D | Realmware Corporation | Arquivos de dados | Visual3D.NET Data File | 3D Object Converter | Open Source |
| .V5D | Open Source | Arquivos de dados | Vis5D Dataset UNIX Chemical | Vis5D | Open Source |
| .V64 | Nintendo | Arquivos de jogos | Nintendo 64 ROM Dump | Project64 | Open Source |
| .VB | Microsoft Corporation | Arquivos de desenvolvedor | Visual Basic Project Item File | Red Dragon | Open Source |
| .VBR | Microsoft Corporation | Arquivos de desenvolvedor | Visual Basic Remote Automation Registration | Linux | Open Source |
| .VC | Software Arts | Arquivos de planilha | VisiCalc Spreadsheet | Verge | Open Source |
| .VCE | Avanset | Arquivos de dados | Visual CertExam Suite Exam File | Audacity | Open Source |
| .VCF | Palm | Arquivos de dados | VCard File | VirtualDub | Open Source |
| .VCH | Wholly Genes, Inc. | Arquivos de dados | Master Genealogist Genealogy Chart | Vocola | Open Source |
| .VCL | Open Source | Arquivos de configuração | Varnish Configuation File | Varnish Cache | Open Source |
| .VDF | Valve | Arquivos de jogos | Valve Data File | VirtualDub | Open Source |
| .VDI | Oracle Corporation | Arquivos de imagem de disco | VirtualBox Virtual Disk Image | StepMania | Open Source |
| .VDR | Avery Dennison | Arquivos de vídeo | VirtualDub Signpost File | VirtualDub | Open Source |
| .VEC | Omron Corporation | Arquivos de imagem vector | CX-Designer Shape File | OpenEmu | Open Source |
| .VERSION | Open Source | Arquivos de dados | Linux GateD Daemon Data | Linux | Open Source |
| .VFK | Sublime HQ Pty Ltd | Arquivos de Texto | Czech Cadastral Exchange Data Format | PSPad | Open Source |
| .VFW | Open Source | Arquivos de vídeo | Video For Windows | Eltima Elmedia Player | Open Source |
| .VGM | Richard Bannister | Arquivos de áudio | Video Game Music File | Audacious | Open Source |
| .VGZ | Various Developers | Arquivos de áudio | Video Game Music Compressed File | Cog | Open Source |
| .VIM | Bram Moolenaar | Arquivos de configuração | Vim Settings File | gVim | Open Source |
| .VLT | zilliondigits | Arquivos codificados | WinVault File Archive | VideoLAN VLC Skin Editor | Open Source |
| .VLW | Open Source | Arquivos de fonte | Processing Font File | Processing | Open Source |
| .VM | Apache HTTP Project Management Committee | Arquivos de desenvolvedor | Velocity Template | Apache Velocity | Open Source |
| .VMD | Open Source | Arquivos de áudio | Covox Raw Sample | Covoxer | Open Source |
| .VMF | Valve | Arquivos de jogos | Valve Map File | Covoxer | Open Source |
| .VMI | Sega | Arquivos de jogos | Dreamcast Doiwnload Info File | Dream Explorer | Open Source |
| .VMS | Sega | Arquivos de dados | Dreamcast VMU Save File | Dream Explorer | Open Source |
| .VMT | VMware | Arquivos de configuração | VMware Configuration File | VTFEdit | Open Source |
| .VNT | Sony | Arquivos de Texto | Sony Ericsson Mobile Phone vNote File | Notepad2 | Open Source |
| .VOB | The DVD Forum | Arquivos de vídeo | DVD Video Object File | Eltima Elmedia Player | Open Source |
| .VOC | Creative Technology Ltd. | Arquivos de áudio | Creative Labs Audio File | AGiliTy | Open Source |
| .VOL | Open Source | Arquivos de jogos | Video Game Archive | Dragon UnPACKer | Open Source |
| .VP | Accellera Systems Initiative | Arquivos codificados | Verilog Encrypted Source Code File | Celestia | Open Source |
| .VPK | Valve | Arquivos de jogos | Valve Pak | GCFScape | Open Source |
| .VPL | Unknown Developer | Arquivos de áudio | Karaoke Player Playlist | vanBasco's Karaoke Player | Open Source |
| .VPM | Garmin | Arquivos de áudio | Garmin Voice File | TTSVoiceEditor | Open Source |
| .VRL | Unknown Developer | Arquivos 3D | VRML World | FreeWRL | Open Source |
| .VRML | Open Source | Arquivos Web | Virtual Reality Modeling Language 3D World | FreeWRL | Open Source |
| .VRO | VideoLAN | Arquivos de vídeo | DVD Video Recording Format | Squared 5 MPEG Streamclip | Open Source |
| .VS | OpenGL | Arquivos 3D | Vertex Shader File | GreekToMe | Open Source |
| .VST | Microsoft Corporation | Arquivos de imagem Raster | Targa Bitmap Image File | Audacity | Open Source |
| .VSY | Open Source | Arquivos Web | VNC Spy Log File | VNC Spy | Open Source |
| .VTF | Valve | Arquivos de jogos | Valve Texture File | VTF Explorer | Open Source |
| .VTS | Intel Corporation | Arquivos de Texto | Intel VTune Program Performance Monitor Project | ParaView | Open Source |
| .VTX | Richard Bannister | Arquivos de áudio | VTX Chiptune File | Audacious | Open Source |
| .VU | Sony | Arquivos de desenvolvedor | Playstation 2 VU Development Source Code | xfit | Open Source |
| .VVF | Open Source | Arquivos de dados | Voc Vocabulary File | Voc | Open Source |
| .WA | Open Source | Arquivos comprimidos | Windows Addon Archive | Win Toolkit | Open Source |
| .WA2 | Midnight Synergy | Arquivos de jogos | Wonderland Adventures Custom Adventure File | Subspace Continuum | Open Source |
| .WAV | Microsoft Corporation | Arquivos de áudio | WAVE Audio File | ModPlug Player | Open Source |
| .WB | Electronic Arts | Arquivos de jogos | FIFA 2000 Game Data | Freelang | Open Source |
| .WB2 | Threefold Photos, Inc. | Arquivos de imagem Raster | Webshots Picture File | Ultimate Webshots Converter | Open Source |
| .WBC | Threefold Photos, Inc. | Arquivos de imagem Raster | Webshots Collection File | Ultimate Webshots Converter | Open Source |
| .WBD | Threefold Photos, Inc. | Arquivos de imagem Raster | Webshots Picture File | Ultimate Webshots Converter | Open Source |
| .WBF | Microsoft Corporation | Arquivos de desenvolvedor | Microsoft Windows Batch File | PSPad | Open Source |
| .WBZ | Threefold Photos, Inc. | Arquivos de imagem Raster | Webshots Download Picture File | Ultimate Webshots Converter | Open Source |
| .WCR | Open Source | Arquivos de configuração | Ergane Configuration File | Ergane | Open Source |
| .WDF | Workshare | Arquivos de dados | Workshare Compare DeltaFile | WiiJManager | Open Source |
de 17 
