| .EAP | Sparx Systems | Arquivos de dados | Enterprise Architect Project | Adobe Photoshop CC | Adobe Systems Incorporated |
| .EBX | IBM | Arquivos de desenvolvedor | Rational Rose 98 Compiled Script | Adobe Creative Suite | Adobe Systems Incorporated |
| .EDB | Microsoft Corporation | Arquivos de banco de dados | Exchange Information Store Database | Adobe Photoshop | Adobe Systems Incorporated |
| .EDD | Adobe Systems Incorporated | Arquivos de dados | Adobe FrameMaker Element Definition Document File | Adobe FrameMaker | Adobe Systems Incorporated |
| .EDL | Avid Technology | Arquivos de vídeo | Edit Decision List File | Adobe Premiere Pro CC | Adobe Systems Incorporated |
| .EDM | Adobe Systems Incorporated | Arquivos de desenvolvedor | Adobe Extension Data Markup Language File | Adobe Dreamweaver | Adobe Systems Incorporated |
| .EDML | Adobe Systems Incorporated | Arquivos de desenvolvedor | Adobe Extension Data Markup Language File | Adobe Dreamweaver | Adobe Systems Incorporated |
| .EDN | Xilinx, Inc. | Arquivos CAD | EDIF Implementation Netlist File | Adobe Acrobat DC | Adobe Systems Incorporated |
| .EDT | Adobe Systems Incorporated | Arquivos eBook | Adobe eBook Download Settings | Adobe Digital Editions | Adobe Systems Incorporated |
| .EMF | Microsoft Corporation | Arquivos de imagem vector | Enhanced Windows Metafile | Adobe Illustrator CC | Adobe Systems Incorporated |
| .EMZ | Microsoft Corporation | Arquivos de imagem vector | Windows Compressed Enhanced Metafile | Adobe Illustrator CC | Adobe Systems Incorporated |
| .ENV | Adobe Systems Incorporated | Arquivos de dados | Adobe Dictionary Data File | Adobe Illustrator CC | Adobe Systems Incorporated |
| .EPR | Adobe Systems Incorporated | Arquivos de configuração | Photoshop AME Preset File | Adobe Photoshop CC | Adobe Systems Incorporated |
| .EPS | Adobe Systems Incorporated | Arquivos de imagem vector | Encapsulated PostScript File | Adobe Illustrator CC | Adobe Systems Incorporated |
| .EPSF | Adobe Systems Incorporated | Arquivos de imagem vector | Encapsulated PostScript Format File | Adobe Illustrator CC | Adobe Systems Incorporated |
| .EPSI | Adobe Systems Incorporated | Arquivos Gráficos | Adobe Encapsulated PostScript Interchange Format | Adobe Photoshop | Adobe Systems Incorporated |
| .EPT | Adobe Systems Incorporated | Arquivos miscelâneas | Adobe Encapsulated PostScript Interchange Format With TIFF Preview | Adobe Acrobat DC | Adobe Systems Incorporated |
| .EPUB | IDPF (International Digital Publishing Forum) | Arquivos eBook | Open eBook File | Adobe InDesign | Adobe Systems Incorporated |
| .ETD | Adobe Systems Incorporated | Arquivos eBook | Adobe Reader EBX Transfer Data File | Adobe Acrobat DC | Adobe Systems Incorporated |
| .EXP | Unknown Developer | Arquivos de desenvolvedor | Symbols Export File | Adobe Acrobat DC | Adobe Systems Incorporated |
| .EXR | Adobe Systems Incorporated | Arquivos de imagem Raster | OpenEXR Image | Adobe Photoshop | Adobe Systems Incorporated |
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