| .SVP | SwiftView, Inc. | Gegevensbestanden | SwiftView Command File | SwiftView | SwiftView, Inc. |
| .SVS | Nintendo | Gegevensbestanden | Game Boy Advance Saved State File | Game Boy Advance | Nintendo |
| .SW0 | National Instruments | Gegevensbestanden | SPICE Sweep Operations Output Data | Spice | National Instruments |
| .SWB | Adobe Systems Incorporated | Gegevensbestanden | Adobe Photoshop Data | Adobe Photoshop | Adobe Systems Incorporated |
| .SWG | Embarcadero Technologies | Gegevensbestanden | SWAG Pascal Snippets | Turbo Pascal | Embarcadero Technologies |
| .SWK | Avanquest Software | Gegevensbestanden | StudyWorks Save File | Studyworks! Teaching Pro: Mathematics Complete | Avanquest Software |
| .SWM | Microsoft Corporation | Gegevensbestanden | Split Windows Imaging Format File | Microsoft ImageX | Microsoft Corporation |
| .SWR | Unknown Developer | Gegevensbestanden | SageWorld Anti-Hacker Program File | Unknown Software | Unknown Developer |
| .SWS | TIBCO Software Inc | Gegevensbestanden | S-PLUS Workspace | TIBCO Spotfire S+ Products | TIBCO Software Inc |
| .SX | Dipl.-Phys.-Ing. Ralf Wirtz | Gegevensbestanden | SimplexNumerica Data File | SimplexNumerica | Dipl.-Phys.-Ing. Ralf Wirtz |
| .SXI | Oracle Corporation | Gegevensbestanden | StarOffice Impress Presentation | Apache OpenOffice | Apache Software Foundation |
| .SY1 | Daichi Laboratory | Gegevensbestanden | Synth 1 Patch File | Synth1 | Daichi Laboratory |
| .SY3 | Harvard Graphics | Gegevensbestanden | Harvard Graphics Symbol File | ACD Systems Canvas | Microsoft Corporation |
| .SYC | The Wireshark Team | Gegevensbestanden | Sniffer Capture File | Wireshark | The Wireshark Team |
| .SYF | SMC Corporation | Gegevensbestanden | SY Configurator Project | SY Configurator | SMC Corporation |
| .SYL | Microsoft Corporation | Gegevensbestanden | Symbolic Link Spreadsheet | Microsoft Excel | Microsoft Corporation |
| .SYLK | Microsoft Corporation | Gegevensbestanden | Microsoft Symbolic Link File | Microsoft Excel | Microsoft Corporation |
| .SYMBOLS | Apple | Gegevensbestanden | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .SYN | Image-Line | Gegevensbestanden | SimSynth Document | FL Studio 12 | Image-Line |
| .SYNC | Apple | Gegevensbestanden | Apple ColorSync File | Apple OS X | Apple |
| .SYNTAX | Apple | Gegevensbestanden | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .SYSLOG | Apple | Gegevensbestanden | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .SZF | Deutsche Automobil Treuhand | Gegevensbestanden | SilverDAT II Data Exchange Format | SilverDAT II | Deutsche Automobil Treuhand |
| .SZP | PKWare | Gegevensbestanden | SecureZIP Policy Data | SecureZIP | PKWare |
| .SZS | Nintendo | Gegevensbestanden | Wii Game Data File | Wiimms SZS Toolset | Nintendo |
| .SZX | Open Source | Gegevensbestanden | Spectaculator ZX-State Snapshot | Spectaculator | Open Source |
| .T | Holt Software | Gegevensbestanden | Turing Source Code File | Holt Software Turing | Holt Software |
| .T01 | H&R Block | Gegevensbestanden | TaxCut 2001 File | H&R Block TaxCut 2001 | H&R Block |
| .T02 | H&R Block | Gegevensbestanden | TaxCut 2002 File | H&R Block TaxCut 2002 | H&R Block |
| .T03 | H&R Block | Gegevensbestanden | TaxCut 2003 File | H&R Block TaxCut 2003 | H&R Block |
| .T05 | H&R Block | Gegevensbestanden | TaxCut 2005 Tax Return Data | TaxCut 2006 | H&R Block |
| .T06 | H&R Block | Gegevensbestanden | TaxCut 2006 Tax Return File | TaxCut 2006 | H&R Block |
| .T10 | H&R Block | Gegevensbestanden | At Home 2010 Tax Return | H&R Block Tax Software | H&R Block |
| .T2 | RM Education | Gegevensbestanden | Textease 2000 File | Textease 2000 | RM Education |
| .T2K | Basement.nl | Gegevensbestanden | Teach2000 Document | Teach2000 | Basement.nl |
| .T2KS | Basement.nl | Gegevensbestanden | Teach2000 Exam Results File | Teach2000 | Basement.nl |
| .T2KT | Basement.nl | Gegevensbestanden | Teach2000 Exam File | Teach2000 | Basement.nl |
| .T2L | Elevenworks LLC | Gegevensbestanden | TouchDraw Library | TouchDraw | Elevenworks LLC |
| .T32 | Symantec Corporation | Gegevensbestanden | Drive Image 5 File | PowerQuest Drive Image | Symantec Corporation |
| .T99 | H&R Block | Gegevensbestanden | TaxCut Data File | TaxCut 2006 | H&R Block |
| .TA0 | TaxAct | Gegevensbestanden | TaxAct 2014 Tax Return File | TaxAct | TaxAct |
| .TA1 | TaxAct | Gegevensbestanden | TaxACT 2001 Tax Form File | TaxAct | TaxAct |
| .TA2 | TaxAct | Gegevensbestanden | TaxAct 2014 Tax Return File | TaxAct | TaxAct |
| .TA3 | TaxAct | Gegevensbestanden | TaxAct 2014 Tax Return File | TaxAct | TaxAct |
| .TA4 | TaxAct | Gegevensbestanden | TaxAct 2014 Tax Return File | TaxAct | TaxAct |
| .TA5 | TaxAct | Gegevensbestanden | TaxAct 2015 Tax Return File | TaxAct | TaxAct |
| .TAB | Microsoft Corporation | Gegevensbestanden | Tab Separated Data File | Microsoft Excel | Microsoft Corporation |
| .TABLE1 | Apple | Gegevensbestanden | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .TABLES | Apple | Gegevensbestanden | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .TAC | Parmerlee, Inc. | Gegevensbestanden | ActiCalc Data File | ActiCalc | Parmerlee, Inc. |
| .TAG | Data Access Worldwide | Gegevensbestanden | DataFlex Data File | DataFlex | Data Access Worldwide |
| .TAH | Borland | Gegevensbestanden | Turbo Assembler Help Data File | Turbo Assembler | Borland |
| .TAI | NVIDIA | Gegevensbestanden | NVIDIA Texture Atlas Creation Tool Texture Data | Texture Atlas Tools | NVIDIA |
| .TAL | Adobe Systems Incorporated | Gegevensbestanden | Adobe TypeAlign Text Illustration File | Adobe TypeAlign | Adobe Systems Incorporated |
| .TALK | Unknown Developer | Gegevensbestanden | Text To Speech File | Unknown Software | Unknown Developer |
| .TALK2 | Apple | Gegevensbestanden | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .TAR | Jean-loup Gailly and Mark Adler | Gegevensbestanden | Consolidated Unix File Archive | 7-Zip | Igor Pavlov |
| .TASK | Hewlett-Packard | Gegevensbestanden | HP Printer Utility Task Plugin File | HP Printer Utility (for Mac) | Hewlett-Packard |
| .TAX | Intuit, Inc. | Gegevensbestanden | TurboTax Tax Return | Intuit Quicken | Quicken |
| .TAX2008 | Intuit, Inc. | Gegevensbestanden | TurboTax 2008 Tax Return | Intuit TurboTax | Intuit, Inc. |
| .TAX2009 | Intuit, Inc. | Gegevensbestanden | TurboTax 2009 Tax Return | Intuit TurboTax | Intuit, Inc. |
| .TAX2010 | Intuit, Inc. | Gegevensbestanden | TurboTax 2010 Tax Return | Intuit TurboTax | Intuit, Inc. |
| .TAX2011 | Intuit, Inc. | Gegevensbestanden | TurboTax 2011 Tax Return | Intuit TurboTax | Intuit, Inc. |
| .TAX2012 | Intuit, Inc. | Gegevensbestanden | TurboTax 2012 Tax Return | Intuit TurboTax | Intuit, Inc. |
| .TAX2013 | Intuit, Inc. | Gegevensbestanden | TurboTax 2013 Tax Return | Intuit TurboTax | Intuit, Inc. |
| .TAX2015 | Intuit, Inc. | Gegevensbestanden | TurboTax 2015 Tax Return | Intuit TurboTax | Intuit, Inc. |
| .TAX2016 | Intuit, Inc. | Gegevensbestanden | TurboTax 2016 Tax Return | Intuit TurboTax | Intuit, Inc. |
| .TB | Tabbery | Gegevensbestanden | Tabbery Tab File | Tabbery | Tabbery |
| .TB3 | Intel Corporation | Gegevensbestanden | Intel VTune Performance Monitor File | Intel VTune | Intel Corporation |
| .TBA | Inmagic | Gegevensbestanden | DB/Text Database Primary Textbase Definition File | DB/TextWorks | Inmagic |
| .TBB | Microsoft Corporation | Gegevensbestanden | Microsoft Office Toolbar Button | Microsoft Office | Microsoft Corporation |
| .TBC | Psygnosis | Gegevensbestanden | Formula One 2001 Season 01 Vehicles Data | Formula One 2001 | Psygnosis |
| .TBF | Trellian Software | Gegevensbestanden | Trellian Button Factory File | Trellian Button Factory | Trellian Software |
| .TBH | PowerBASIC, Inc. | Gegevensbestanden | Turbo Basic Help File | PowerBASIC | PowerBASIC, Inc. |
| .TBI | Electronic Arts | Gegevensbestanden | FIFA 2001 Game Data | FIFA 2001 | EA Sports |
| .TBK | SumTotal Systems | Gegevensbestanden | ToolBook Project File | ToolBook | SumTotal Systems |
| .TBL | Blizzard Entertainment Inc. | Gegevensbestanden | StarCraft Information Table | StarCraft | Blizzard Entertainment Inc. |
| .TBT | ARRIS | Gegevensbestanden | Timbuktu Pro Remote Control Software File Format | Timbuktu | ARRIS |
| .TBV | Brain Innovation | Gegevensbestanden | Turbo-BrainVoyager Data File | Turbo-BrainVoyager | Brain Innovation |
| .TBX | Simple DirectMedia Layer (SDL) | Gegevensbestanden | SDL Trados Studio Glossary Data | Sublime Text | Sublime HQ Pty Ltd |
| .TC | TrueCrypt | Gegevensbestanden | TrueCrypt Volume | TrueCrypt | TrueCrypt |
| .TCC | Pro Systems | Gegevensbestanden | TimeCalc Classic Data File | TimeCalc Classic | Pro Systems |
| .TCH | Micro Focus International plc | Gegevensbestanden | Borland C++ Help Document | Borland C++ | Micro Focus International plc |
| .TCL | Open Source | Gegevensbestanden | Tcl Script | MacroMates TextMate | MacroMates |
| .TCO | Unknown Developer | Gegevensbestanden | T9000 Object Module | Unknown Software | Unknown Developer |
| .TCX | Garmin | Gegevensbestanden | Training Center Database File | Garmin Connect | Garmin |
| .TDB | Google | Gegevensbestanden | Android Thumbnail Cache | Google Android | Google |
| .TDD | MRDC Software | Gegevensbestanden | Tables Direct Template | Tables Direct | MRDC Software |
| .TDF | DVD Copy | Gegevensbestanden | Title Definition Format File | DVD X Copy | DVD Copy |
| .TDG | Tom Lachecki | Gegevensbestanden | Tree Diagram Generator Document | Tree Diagram Generator | Tom Lachecki |
| .TDH | Borland | Gegevensbestanden | Turbo Debugger Help File | Borland Turbo Debugger | Borland |
| .TDK | Borland | Gegevensbestanden | Borland Turbo Debugger Keystroke Recording File | Borland Turbo Debugger | Borland |
| .TDN | SoftArtStudio | Gegevensbestanden | TreeDBNotes Database | TreeDBNotes | SoftArtStudio |
| .TDR | PO KSI | Gegevensbestanden | ArVid Tape Backup | ArVid | PO KSI |
| .TDT | Sony | Gegevensbestanden | AVCHD Thumbnail File | Unknown Software | Unknown Developer |
| .TDX | D-TEG Security Co. | Gegevensbestanden | D-TEG CCTV Video Information File | D-TEG MRX PC Client | D-TEG Security Co. |
| .TEASERS2 | Apple | Gegevensbestanden | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .TEC | SIL International | Gegevensbestanden | TECkit Compiled Mapping File | TECkit | SIL International |
| .TECH | Apple | Gegevensbestanden | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .TEF | tabledit.com | Gegevensbestanden | TablEdit Tablature | TuxGuitar | Julian Gabriel Casadesus and Others |
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