| .QLC | Adobe Systems Incorporated | Gegevensbestanden | Adobe PostScript Help File | Adobe Creative Suite | Adobe Systems Incorporated |
| .QT | Apple | Videobestanden | Apple QuickTime Movie | Adobe Flash Player | Adobe Systems Incorporated |
| .QTI | Apple | Rasterafbeeldingen | QuickTime Image File | Adobe Flash Professional CC | Adobe Systems Incorporated |
| .QTIF | Apple | Rasterafbeeldingen | QuickTime Image File | Adobe Flash Professional CC | Adobe Systems Incorporated |
| .QTM | Apple | Videobestanden | Apple QuickTime Movie | Adobe Flash Player | Adobe Systems Incorporated |
| .QXD | Quark Software Inc. | Pagina-indelingsbestand | QuarkXPress Document | Adobe InDesign | Adobe Systems Incorporated |
| .QXT | Quark Software Inc. | Pagina-indelingsbestand | QuarkXPress Template | Adobe InDesign | Adobe Systems Incorporated |
| .R3D | Various Developers | Videobestanden | REDCODE Video File | Adobe Premiere Pro CC | Adobe Systems Incorporated |
| .RAF | Fuji Xerox | Raw-Bestanden Voor Camera | Fuji RAW Image File | Adobe Photoshop Elements | Adobe Systems Incorporated |
| .RAW | Unknown Developer | Raw-Bestanden Voor Camera | Raw Image Data File | Adobe Photoshop Elements | Adobe Systems Incorporated |
| .RDT | Adobe Systems Incorporated | Gegevensbestanden | Adobe Captivate RoboDemo Template File | Adobe Captivate | Adobe Systems Incorporated |
| .RF | Adobe Systems Incorporated | Gegevensbestanden | Adobe FrameMaker Document | Adobe FrameMaker | Adobe Systems Incorporated |
| .RFR | Adobe Systems Incorporated | Gegevensbestanden | Adobe Photoshop Frame Filter | Adobe Photoshop | Adobe Systems Incorporated |
| .RL4 | Various Developers | Rasterafbeeldingen | Bitmap Image File | Adobe Illustrator CC | Adobe Systems Incorporated |
| .RL8 | Microsoft Corporation | Grafische Bestanden | Windows Bitmap Image | Adobe Photoshop | Adobe Systems Incorporated |
| .RLE | Various Developers | Rasterafbeeldingen | Run Length Encoded Bitmap | Adobe Photoshop Elements | Adobe Systems Incorporated |
| .RMD | Thomson Reuters Corporation | Gegevensbestanden | Reference Manager Data File | Adobe Premiere Pro CC | Adobe Systems Incorporated |
| .RMF | Valve | Spelbestanden | Hammer Rich Map Format | Adobe Acrobat DC | Adobe Systems Incorporated |
| .RPF | Rockstar Games | Spelbestanden | Grand Theft Auto Data File | Adobe After Effects | Adobe Systems Incorporated |
| .RPLN | Adobe Systems Incorporated | Plug-inbestanden | InDesign Required Plug-in File | Adobe InDesign | Adobe Systems Incorporated |
| .RSA | Various Developers | Allerlei bestanden | RSA Certificate File | Adobe Photoshop Elements | Adobe Systems Incorporated |
| .RTA | Adobe Systems Incorporated | Gegevensbestanden | RoboHelp RTA Data File | Adobe RoboHelp | Adobe Systems Incorporated |
| .RTK | Adobe Systems Incorporated | Gegevensbestanden | Adobe RoboHelp Configuration File | Adobe RoboHelp | Adobe Systems Incorporated |
| .RVL | muvee | Videobestanden | Muvee Reveal X Project File | Adobe Revel | Adobe Systems Incorporated |
| .RWL | Leica Biosystems | Raw-Bestanden Voor Camera | Leica D-Lux 4 RAW Image | Adobe Photoshop | Adobe Systems Incorporated |
| .SAT | Spatial Corp | CAD-bestanden | ACIS SAT 3D Model File | Adobe Acrobat DC | Adobe Systems Incorporated |
| .SBL | Adobe Systems Incorporated | Grafische Bestanden | Shockwave Flash Object | Adobe Flash Player | Adobe Systems Incorporated |
| .SBX | Dream Design Entertainment Software | Gecomprimeerde bestanden | GLBasic Shoebox File | Adobe Illustrator CC | Adobe Systems Incorporated |
| .SCM | Gimpel Software | Plug-inbestanden | GIMP Script-Fu Script | ExtendScript Toolkit (ESTK) | Adobe Systems Incorporated |
| .SCSS | Sublime HQ Pty Ltd | Webbestanden | Syntactically Awesome Stylesheets Syntax Data | Adobe Dreamweaver | Adobe Systems Incorporated |
| .SCT | Scitex | Rasterafbeeldingen | Scitex Continuous Tone File | Adobe Photoshop | Adobe Systems Incorporated |
| .SD0 | Adobe Systems Incorporated | Raw-Bestanden Voor Camera | Dali Raw Image | Adobe Lightroom CC | Adobe Systems Incorporated |
| .SD1 | Adobe Systems Incorporated | Raw-Bestanden Voor Camera | Dali Raw Image | Adobe Lightroom CC | Adobe Systems Incorporated |
| .SEQU | Adobe Systems Incorporated | Instellingsbestanden | Adobe Acrobat Sequence File | Adobe Acrobat DC | Adobe Systems Incorporated |
| .SES | Adobe Systems Incorporated | Audiobestanden | Audition Session File | Adobe Audition | Adobe Systems Incorporated |
| .SESSION | Dassault Systèmes | 3D-bestanden | CATIA 4 Session File | Adobe Acrobat DC | Adobe Systems Incorporated |
| .SGM | VBA Team | Spelbestanden | VisualBoyAdvance Saved Game | Adobe FrameMaker | Adobe Systems Incorporated |
| .SGML | Corel | Gegevensbestanden | Standard Generalized Markup Language File | Adobe FrameMaker | Adobe Systems Incorporated |
| .SHC | Adobe Systems Incorporated | Gegevensbestanden | Adobe Photoshop Contours File | Adobe Photoshop CC | Adobe Systems Incorporated |
| .SHH | Adobe Systems Incorporated | Instellingsbestanden | Adobe Photoshop Shadow/Highlight Settings | Adobe Photoshop CC | Adobe Systems Incorporated |
| .SHTM | Opera Software | Videobestanden | HTML Server Side Include File | Adobe Dreamweaver | Adobe Systems Incorporated |
| .SHTML | Sublime HQ Pty Ltd | Webbestanden | Server Side Include HTML File | Adobe Dreamweaver | Adobe Systems Incorporated |
| .SITE | Adobe Systems Incorporated | Webbestanden | GoLive Website Project File | Adobe GoLive | Adobe Systems Incorporated |
| .SIV | Adobe Systems Incorporated | Videobestanden | Silicon Imaging Video File | Adobe SpeedGrade | Adobe Systems Incorporated |
| .SKL | Autodesk, Inc. | 3D-bestanden | Maya Skeleton File | Adobe Authorware | Adobe Systems Incorporated |
| .SLDASM | Dassault Systèmes | CAD-bestanden | SolidWorks Assembly File | Adobe Acrobat DC | Adobe Systems Incorporated |
| .SLDPRT | Dassault Systèmes | CAD-bestanden | SolidWorks CAD Part File | Adobe Acrobat DC | Adobe Systems Incorporated |
| .SMP | MakeMusic, Inc. | Audiobestanden | SmartMusic Performance File | Adobe Audition | Adobe Systems Incorporated |
| .SND | Open Source | Audiobestanden | Sound File | Adobe Audition | Adobe Systems Incorporated |
| .SOL | Adobe Systems Incorporated | Instellingsbestanden | Flash Local Shared Object File | Adobe Flash Player | Adobe Systems Incorporated |
| .SOR | Adobe Systems Incorporated | Gegevensbestanden | Adobe Flash Media Server File System Object | Adobe Media Server | Adobe Systems Incorporated |
| .SPL | Microsoft Corporation | Systeembestanden | Windows Print Spool File | Adobe Flash Player | Adobe Systems Incorporated |
| .SR2 | Sony | Raw-Bestanden Voor Camera | Sony RAW Image | Adobe Photoshop | Adobe Systems Incorporated |
| .SRF | NewTek | 3D-bestanden | LightWave Surface File | Adobe Photoshop | Adobe Systems Incorporated |
| .SRW | Samsung Electronics | Raw-Bestanden Voor Camera | Samsung RAW Image | Adobe Photoshop Elements | Adobe Systems Incorporated |
| .SSI | Adobe Systems Incorporated | Ontwikkelaarsbestanden | Adobe Dreamweaver Server Side Include File | Adobe Dreamweaver | Adobe Systems Incorporated |
| .SSK | Adobe Systems Incorporated | Vectorafbeeldingen | SmartSketch 95 Document | Adobe Flash Professional CC | Adobe Systems Incorporated |
| .STC | Adobe Systems Incorporated | Webbestanden | Contribute Connection Key File | Adobe Contribute 6.5 | Adobe Systems Incorporated |
| .STD | Oracle Corporation | Vectorafbeeldingen | Apache OpenOffice Drawing Template | Adobe Acrobat DC | Adobe Systems Incorporated |
| .STE | Adobe Systems Incorporated | Instellingsbestanden | Dreamweaver Site Settings File | Adobe Dreamweaver | Adobe Systems Incorporated |
| .STL | 3D Systems | CAD-bestanden | Stereolithography File | Adobe Fireworks | Adobe Systems Incorporated |
| .STM | Microsoft Corporation | Gegevensbestanden | Exchange Streaming Media File | Adobe Dreamweaver | Adobe Systems Incorporated |
| .STN | ON1, Inc. | Vectorafbeeldingen | Genuine Fractals Image | Adobe Photoshop | Adobe Systems Incorporated |
| .STP | Unknown Developer | 3D-bestanden | STEP 3D CAD File | Adobe RoboHelp | Adobe Systems Incorporated |
| .SVG | Nintendo | Spelbestanden | Saved Game File | Adobe Illustrator CC | Adobe Systems Incorporated |
| .SVGZ | Adobe Systems Incorporated | Vectorafbeeldingen | Compressed SVG File | Adobe Illustrator CC | Adobe Systems Incorporated |
| .SWA | Adobe Systems Incorporated | Audiobestanden | Shockwave Audio | Adobe Director | Adobe Systems Incorporated |
| .SWB | Adobe Systems Incorporated | Gegevensbestanden | Adobe Photoshop Data | Adobe Photoshop | Adobe Systems Incorporated |
| .SWC | Adobe Systems Incorporated | Ontwikkelaarsbestanden | Flex Components Archive | Adobe Animate CC 2017 | Adobe Systems Incorporated |
| .SWD | Adobe Systems Incorporated | Ontwikkelaarsbestanden | Flash Debug File | Adobe Flash Player | Adobe Systems Incorporated |
| .SWF | Adobe Systems Incorporated | Videobestanden | Shockwave Flash Movie | Adobe Animate CC 2017 | Adobe Systems Incorporated |
| .SWL | Macromedia | Grafische Bestanden | Alternate Macromedia Flash Format | Adobe Flash Player | Adobe Systems Incorporated |
| .SWT | Adobe Systems Incorporated | Videobestanden | Flash Generator Template | Adobe Flash Professional CC | Adobe Systems Incorporated |
| .SWZ | Adobe Systems Incorporated | Webbestanden | Adobe Flash Player Cache File | Adobe Flash Player | Adobe Systems Incorporated |
| .SYN | Image-Line | Audiobestanden | SimSynth Document | Adobe RoboHelp | Adobe Systems Incorporated |
| .T3D | Epic Games | 3D-bestanden | Unreal Engine 3D Object File | Adobe Flash Player | Adobe Systems Incorporated |
| .TAL | Adobe Systems Incorporated | Tekstbestanden | Adobe TypeAlign Text Illustration File | Adobe TypeAlign | Adobe Systems Incorporated |
| .TBL | Blizzard Entertainment Inc. | Gegevensbestanden | StarCraft Information Table | Adobe PageMaker | Adobe Systems Incorporated |
| .TBR | Adobe Systems Incorporated | Instellingsbestanden | Adobe Photoshop Custom Toolbar Preset | Adobe Photoshop | Adobe Systems Incorporated |
| .TCL | Open Source | Ontwikkelaarsbestanden | Tcl Script | ExtendScript Toolkit (ESTK) | Adobe Systems Incorporated |
| .TGA | Avid Technology | Rasterafbeeldingen | Targa Graphic | Adobe Illustrator CC | Adobe Systems Incorporated |
| .THM | Sony | Allerlei bestanden | Sony Ericsson Mobile Phone Theme File | Adobe Photoshop Elements | Adobe Systems Incorporated |
| .TIF | XnSoft | Rasterafbeeldingen | Tagged Image File Format | Adobe Illustrator CC | Adobe Systems Incorporated |
| .TIFF | XnSoft | Rasterafbeeldingen | Tagged Image File Format | Adobe Illustrator CC | Adobe Systems Incorporated |
| .TIM | Sierra Entertainment | Spelbestanden | The Incredible Machine Level | Adobe Illustrator CC | Adobe Systems Incorporated |
| .TOD | JVCKenwood Group | Videobestanden | JVC Everio Video Capture File | Adobe Flash Player | Adobe Systems Incorporated |
| .TPL | Unknown Developer | Tekstbestanden | Document Template | Adobe Photoshop | Adobe Systems Incorporated |
| .TTY | Adobe Systems Incorporated | Gegevensbestanden | Adobe Dreamweaver Data | Adobe Dreamweaver | Adobe Systems Incorporated |
| .U3D | 3D Industry Forum | 3D-bestanden | Universal 3D File | Adobe Acrobat DC | Adobe Systems Incorporated |
| .VB | Microsoft Corporation | Ontwikkelaarsbestanden | Visual Basic Project Item File | Adobe Dreamweaver | Adobe Systems Incorporated |
| .VBS | Microsoft Corporation | Uitvoerbare bestanden | VBScript File | Adobe Dreamweaver | Adobe Systems Incorporated |
| .VCE | Avanset | Gegevensbestanden | Visual CertExam Suite Exam File | Adobe Audition | Adobe Systems Incorporated |
| .VDA | Microsoft Corporation | Rasterafbeeldingen | Targa Bitmap Image File | Adobe Illustrator CC | Adobe Systems Incorporated |
| .VMC | Microsoft Corporation | Instellingsbestanden | Windows Virtual Machine Configuration File | Adobe Acrobat DC | Adobe Systems Incorporated |
| .VOC | Creative Technology Ltd. | Audiobestanden | Creative Labs Audio File | Adobe Audition | Adobe Systems Incorporated |
| .VOX | Ken Silverman | 3D-bestanden | Voxlap Voxel Model File | Adobe Audition | Adobe Systems Incorporated |
| .VPH | optikVerve Labs | Instellingsbestanden | VirtualPhotographer Custom Settings | Adobe Photoshop | Adobe Systems Incorporated |
| .VPR | Adobe Systems Incorporated | Gegevensbestanden | Adobe Premiere Preset | Adobe Premiere Pro CC | Adobe Systems Incorporated |
| .VST | Microsoft Corporation | Rasterafbeeldingen | Targa Bitmap Image File | Adobe Illustrator CC | Adobe Systems Incorporated |
| .VTM | Adobe Systems Incorporated | Ontwikkelaarsbestanden | Visual Tool Markup Language Document | Adobe Dreamweaver | Adobe Systems Incorporated |
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