| .VBOX | Oracle Corporation | File di settaggi | Oracle VM VirtualBox Settings File | Oracle VM VirtualBox | Oracle Corporation |
| .VCA | Interscape | File di settaggi | VAKCER Project Tracker Add-in | VAKCER Project Tracker | Interscape |
| .VCF | Palm | File di settaggi | VCard File | Microsoft Outlook Express | Microsoft Corporation |
| .VCL | Open Source | File di settaggi | Varnish Configuation File | Varnish Cache | Open Source |
| .VCPREF | Symantec Corporation | File di settaggi | Norton Antivirus Preferences File | Norton Security | Symantec Corporation |
| .VCW | Microsoft Corporation | File di settaggi | eMbedded Visual C++ Workspace File | Microsoft Visual Studio | Microsoft Corporation |
| .VFO | Silicon Graphics, Inc. | File di settaggi | Silicon Graphics Onyx2 Video Format Combiner File | Video Format Combiner | Silicon Graphics, Inc. |
| .VIM | Bram Moolenaar | File di settaggi | Vim Settings File | Vim | Bram Moolenaar |
| .VLT | zilliondigits | File di settaggi | WinVault File Archive | WinVault | zilliondigits |
| .VMC | Microsoft Corporation | File di settaggi | Windows Virtual Machine Configuration File | VMware Workstation | VMware |
| .VMT | VMware | File di settaggi | VMware Configuration File | VMware Workstation | VMware |
| .VMTM | VMware | File di settaggi | VMware Team Data File | VMware Workstation | VMware |
| .VMX | VMware | File di settaggi | VMware Configuration File | VMware Workstation | VMware |
| .VMXF | VMware | File di settaggi | VMware Team Member File | VMware Workstation | VMware |
| .VPH | optikVerve Labs | File di settaggi | VirtualPhotographer Custom Settings | Adobe Photoshop | Adobe Systems Incorporated |
| .VPL | Unknown Developer | File di settaggi | Karaoke Player Playlist | vanBasco's Karaoke Player | Open Source |
| .VPS | H+H Software GmbH | File di settaggi | Virtual CD Copy Template | H+H Software Virtual CD | H+H Software GmbH |
| .VQS | Datapath | File di settaggi | Datapath X4 Configuration File | Datapath X4 | Datapath |
| .VRE | ASG Technologies | File di settaggi | ASG Remote Desktop Settings | ASG-Remote Desktop | ASG Technologies |
| .VRP | Incendo Technology | File di settaggi | Vectir Profile Template File | Vectir | Incendo Technology |
| .VSC | McAfee, Inc. | File di settaggi | McAfee VirusScan Configuration File | McAfee VirusScan Enterprise | McAfee, Inc. |
| .VSIXLANGPACK | Microsoft Corporation | File di settaggi | Microsoft Visual Studio Localised VSIX Package | Microsoft Visual Studio | Microsoft Corporation |
| .VSPROPS | Microsoft Corporation | File di settaggi | Microsoft Visual Studio Project Property Sheet File | Microsoft Visual Studio | Microsoft Corporation |
| .VSPSCC | Microsoft Corporation | File di settaggi | Visual Studio Project Source Control Data | Microsoft Visual Studio | Microsoft Corporation |
| .VSSETTINGS | Microsoft Corporation | File di settaggi | Visual Studio Settings File | Microsoft Visual Studio | Microsoft Corporation |
| .VSW | Microsoft Corporation | File di settaggi | Visio Workspace File | Microsoft Visio 2016 | Microsoft Corporation |
| .VUE | E-on Software, Inc. | File di settaggi | Vue Scene File | E-on Vue | E-on Software, Inc. |
| .VUI | Jeppesen Marine, Inc. | File di settaggi | Visual Navigation Suite Exported Settings | Visual Navigation Suite | Jeppesen Marine, Inc. |
| .VWP | Raven software | File di settaggi | Vehicle Weapon File | Raven Software Star Wars Jedi Knight: Jedi Academy | Valve |
| .VXP | Interscape | File di settaggi | Mobile Application File | Mediatek MRE SDK | MediaTek |
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