| .PIF | Microsoft Corporation | File eseguibili | Program Information File | Microsoft Windows | Microsoft Corporation |
| .PKGLIST | Pepper Computer | File eseguibili | Pepper Keeper Package Installation File | Pepper Keeper | Pepper Computer |
| .PLSC | Microsoft Corporation | File eseguibili | Messenger Plus! Live Script File | Microsoft Windows Live Messenger | Microsoft Corporation |
| .PLX | ActiveState | File eseguibili | Perl Executable File | BBEdit | Bare Bones Software |
| .PRC | Adobe Systems Incorporated | File eseguibili | Product Representation Compact File | Adobe Acrobat DC | Adobe Systems Incorporated |
| .PRG | Open Source | File eseguibili | Program File | Notepad++ | Don Ho |
| .PRX | Microsoft Corporation | File eseguibili | FoxPro Compiled Program | Microsoft Visual FoxPro | Microsoft Corporation |
| .PVA | Hauppauge Computer Works | File eseguibili | Hauppauge DVB-Software File | Hauppauge DVB-Software | Hauppauge Computer Works |
| .PVD | Varden Development | File eseguibili | Polygen3D Vector Descriptor | Polygen3D | Varden Development |
| .PWC | LANovation | File eseguibili | PictureTaker File | LANovation PictureTaker | LANovation |
| .PYC | Python Software Foundation | File eseguibili | Python Compiled File | Python | Python Software Foundation |
| .PYO | Python Software Foundation | File eseguibili | Python Optimized Code | Python | Python Software Foundation |
| .QDE | Microsoft Corporation | File eseguibili | QDOS Executable | MS-DOS | Microsoft Corporation |
| .QPX | Microsoft Corporation | File eseguibili | FoxPro Compiled Query Program | Microsoft Visual FoxPro | Microsoft Corporation |
| .RBX | IBM | File eseguibili | Rembo-C Compiled Script | Rembo Toolkit | Open Source |
| .RGS | Microsoft Corporation | File eseguibili | Registry Script | Microsoft Visual Studio | Microsoft Corporation |
| .ROB | WinTask | File eseguibili | WinTask Compiled Executable | WinTask | WinTask |
| .ROX | Sonic Solutions | File eseguibili | Roxio Project File | Roxio Creator NXT Pro 6 | Roxio |
| .RPJ | Uni Comp | File eseguibili | Real Pac Batch Job File | Real Pac | Uni Comp |
| .RTL | Hewlett-Packard | File eseguibili | Raster Transfer Language File | SwiftView | SwiftView, Inc. |
| .RUN | Open Source | File eseguibili | Linux Executable File | Linux | Open Source |
| .RXE | The LEGO Group | File eseguibili | Lego Mindstorms NXT Executable Program | LEGO MINDSTORMS NXT | The LEGO Group |
| .SB4 | Lindersoft | File eseguibili | SetupBuilder Installation Project | SetupBuilder | Lindersoft |
| .SBS | Allegorithmic | File eseguibili | Substance Package | Substance Designer | Allegorithmic |
| .SCA | Symantec Corporation | File eseguibili | Norton AntiVirus Scan File | Norton Antivirus | Symantec Corporation |
| .SCAR | Interscape | File eseguibili | SCAR Script File | SCAR | Interscape |
| .SCB | Scala | File eseguibili | Scala Published Script | Scala Designer | Scala |
| .SCPT | Apple | File eseguibili | AppleScript Script File | MacroMates TextMate | MacroMates |
| .SCR | Microsoft Corporation | File eseguibili | Windows Screensaver File | Microsoft Windows | Microsoft Corporation |
| .SCRIPT | Unknown Developer | File eseguibili | Generic Script File | LibreOffice | The Document Foundation |
| .SCT | Scitex | File eseguibili | Scitex Continuous Tone File | Adobe Photoshop | Adobe Systems Incorporated |
| .SEED | Open Source | File eseguibili | Linux Preseed File | Ubuntu | Open Source |
| .SFL | Magix Software GmbH | File eseguibili | Sound Forge Pro Sound Data File | MAGIX Vegas | Magix Software GmbH |
| .SHB | Microsoft Corporation | File eseguibili | Windows Document Shortcut | Microsoft Windows | Microsoft Corporation |
| .SMM | Samsung Electronics | File eseguibili | Samsung Memo File | Samsung Kies | Samsung Electronics |
| .SOM | Corel | File eseguibili | Corel Paradox Sort Information | Corel Paradox | Corel |
| .SPR | Valve | File eseguibili | Half-Life Sprite File | Half-Life | Valve |
| .SW0 | National Instruments | File eseguibili | SPICE Sweep Operations Output Data | Spice | National Instruments |
| .SXX | SAS Institute Inc. | File eseguibili | SAS Stat Studio Module Executable | SAS | SAS Institute Inc. |
| .THM | Sony | File eseguibili | Sony Ericsson Mobile Phone Theme File | Sony Ericsson Theme Creator | Sony Mobile Communications |
| .TMS | Telemate | File eseguibili | Telemate Script | Telemate | Telemate |
| .TZX | Kromasoft | File eseguibili | Tanzzle Graphic Object File | Tanzzle Game | Kromasoft |
| .U3P | SanDisk Corporation | File eseguibili | U3 Platform Install Data File | WinZip | Corel |
| .U4A | Unknown Developer | File eseguibili | UnInstaller Archive File | Unknown Software | Unknown Developer |
| .UDF | Open Source | File eseguibili | Universal Disk Format Image File | 7-Zip | Igor Pavlov |
| .VBE | Microsoft Corporation | File eseguibili | VBScript Encoded Script File | Microsoft Visual Studio | Microsoft Corporation |
| .VBS | Microsoft Corporation | File eseguibili | VBScript File | Microsoft Notepad | Microsoft Corporation |
| .VDO | Unknown Developer | File eseguibili | Heathen Virus File | Unknown Software | Unknown Developer |
| .VLX | Autodesk, Inc. | File eseguibili | Compiled AutoLISP File | Autodesk AutoCAD Ecscad | Autodesk, Inc. |
| .VPM | Garmin | File eseguibili | Garmin Voice File | TTSVoiceEditor | Open Source |
| .VXP | Interscape | File eseguibili | Mobile Application File | Mediatek MRE SDK | MediaTek |
| .WCM | Corel | File eseguibili | WordPerfect Macro | Corel WordPerfect X8 | Corel |
| .WIDGET | Microsoft Corporation | File eseguibili | Microsoft Windows Mobile Widget | Microsoft Visual Studio | Microsoft Corporation |
| .WIZ | Microsoft Corporation | File eseguibili | Microsoft Wizard File | Microsoft Word | Microsoft Corporation |
| .WORKFLOW | Apple | File eseguibili | Automator Workflow | Apple Automator | Apple |
| .WPK | Corel | File eseguibili | WordPerfect Macro | Corel WordPerfect X8 | Corel |
| .WS | MicroPro International Corp. | File eseguibili | WordStar Document | Corel WordPerfect X8 | Corel |
| .WSF | Microsoft Corporation | File eseguibili | Windows Script File | Notepad++ | Don Ho |
| .WSH | Microsoft Corporation | File eseguibili | Windows Script Host Settings File | Microsoft Notepad | Microsoft Corporation |
| .XAP | Microsoft Corporation | File eseguibili | XACT Project | Microsoft XACT | Microsoft Corporation |
| .XBAP | Microsoft Corporation | File eseguibili | XAML Browser Application File | Microsoft Visual Studio | Microsoft Corporation |
| .XLM | Microsoft Corporation | File eseguibili | Excel Macro | Microsoft Excel | Microsoft Corporation |
| .XQT | CA Technologies | File eseguibili | SuperCalc Macro File | SuperCalc | CA Technologies |
| .XYS | Donald Lessau | File eseguibili | XYplorer Script File | XYplorer | Donald Lessau |
| .ZL9 | ZoneAlarm | File eseguibili | ZoneAlarm Quarantined EXE File | ZoneAlarm Antivirus | Check Point Software Technologies Ltd. |
| .ZPKG | Zyxel Communications | File eseguibili | Zyxel NSA-32x Application Package | Unknown Software | Unknown Developer |
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