| .MUX | Ubisoft | Fichiers audio | Trackmania Music File | TrackMania | Nadeo |
| .MUZ | HoverDesk.net | Fichiers audio | MUZ Audio File | Audacity | Open Source |
| .MV3 | Unknown Developer | Fichiers audio | Audio Data | Unknown Software | Unknown Developer |
| .MW_ | Unknown Developer | Fichiers audio | Audio Utility Midimach Compressed File | Unknown Software | Unknown Developer |
| .MX3 | Acoustica, Inc. | Fichiers audio | Mixcraft 3 Audio Project | Acoustica Mixcraft | Acoustica, Inc. |
| .MXL | Michael Good | Fichiers audio | Compressed MusicXML File | MuseScore | Open Source |
| .MXMF | Nokia | Fichiers audio | Mobile XMF Ringtone File | Nokia Audio Suite | Nokia |
| .MYR | Myriad Software | Fichiers audio | Myriad Music File | Myriad Melody Assistant | Myriad Software |
| .MZ | David Webber | Fichiers audio | Mozart Compressed File | Mozart | David Webber |
| .MZP | Autodesk, Inc. | Fichiers audio | MAXScript Zip Package | Autodesk 3ds Max | Autodesk, Inc. |
| .NAK | Unknown Developer | Fichiers audio | Older Version Audio File | Unknown Software | Unknown Developer |
| .NAP | McAfee, Inc. | Fichiers audio | McAfee ePO Network Associates Package | McAfee ePolicy Orchestrator | McAfee, Inc. |
| .NCH | Microsoft Corporation | Fichiers audio | On Hold Message/Music File | Microsoft Outlook Express | Microsoft Corporation |
| .NIFF | Personal Composer | Fichiers audio | Notation Interchange File Format | Personal Composer | Personal Composer |
| .NIST | Machine Intelligence Laboratory | Fichiers audio | HTK NIST Audio Data | Awave Studio | FMJ-Software |
| .NKC | Native Instruments | Fichiers audio | Kontakt Library Data File | Native Instruments Kontakt | Native Instruments |
| .NKI | Native Instruments | Fichiers audio | KONTAKT Instrument File | Native Instruments Kontakt | Native Instruments |
| .NKM | Native Instruments | Fichiers audio | Kontakt Multi Instrument File | Native Instruments Kontakt | Native Instruments |
| .NKS | Native Instruments | Fichiers audio | Kontakt Monolith Container | Native Instruments Kontakt | Native Instruments |
| .NML | Native Instruments | Fichiers audio | Traktor Collection File | Traktor | Native Instruments |
| .NOKIA | Nokia | Fichiers audio | Nokia Proprietary Ringtone | Nokia PC Suite | Nokia |
| .NOTE | Failsafe Games | Fichiers audio | Notessimo Composition | Notessimo | Starburst |
| .NPL | Nokia | Fichiers audio | Nokia Playlist File | Nokia Multimedia Player | Nokia |
| .NRA | Nero AG | Fichiers audio | Nero Audio Compilation | Nero 2017 | Nero AG |
| .NRT | Nokia | Fichiers audio | Nokia Ringtone | Nokia Suite | Nokia |
| .NSA | Nullsoft | Fichiers audio | Nullsoft Streaming Audio File | Nullsoft Winamp | Nullsoft |
| .NSF | Unknown Developer | Fichiers audio | NES Sound Format File | DeliPlayer | Open Source |
| .NSP | PENTAX Medical | Fichiers audio | Computerized Speech Lab Audio Speech Format | Computerized Speech Lab | PENTAX Medical |
| .NST | Microsoft Corporation | Fichiers audio | Outlook Connector For Notes File | Microsoft Outlook | Microsoft Corporation |
| .NTN | NOTION Music, Inc. | Fichiers audio | NOTION Song File | VirtuosoWorks NOTION | NOTION Music, Inc. |
| .NTW | NoteWorthy Software | Fichiers audio | Noteworthy Composer Song File | NoteWorthy Composer | NoteWorthy Software |
| .NVF | Creative Technology Ltd. | Fichiers audio | Creative Labs NVF Audio File | Apple iTunes | Apple |
| .NWC | NoteWorthy Software | Fichiers audio | NoteWorthy Composer File | NoteWorthy Composer | NoteWorthy Software |
| .NWI | Clavia DMI AB | Fichiers audio | Nord Wave Manager Instrument Sample | Nord Sound Manager | Clavia DMI AB |
| .NXT | NeXT | Fichiers audio | NeXTSTEP Sound Format | NeXTSTEP | NeXT |
| .OBW | Toontrack | Fichiers audio | Superior Drummer Sounds File | Superior Drummer | Toontrack |
| .OCDF | Recorded Books | Fichiers audio | OneClickDigital MP3 Audio Book | OneClickDigital | Recorded Books |
| .ODD | Coby Electronics Corporation | Fichiers audio | Coby Voice Recorder Data | Coby Voice Manager Software | Coby Electronics Corporation |
| .ODM | Open Source | Fichiers audio | OpenDocument Master Document | Apache OpenOffice | Apache Software Foundation |
| .OFS | Florin Ghido | Fichiers audio | OptimFROG Dualstream Data | Nullsoft Winamp | Nullsoft |
| .OGA | Xiph.Org | Fichiers audio | Ogg Vorbis Audio File | VLC Media Player | VideoLAN |
| .OGG | Xiph.Org | Fichiers audio | Ogg Vorbis Audio File | VLC Media Player | VideoLAN |
| .OKT | Open Source | Fichiers audio | Oktalyzer Module | ModPlug Player | Open Source |
| .OLV | Unknown Developer | Fichiers audio | OnLive! Traveler Sound File | Unknown Software | Unknown Developer |
| .OMA | Sony | Fichiers audio | Sony OpenMG Music File | Sony SonicStage | Sony |
| .OMF | Avid Technology | Fichiers audio | Open Media Framework File | Steinberg Cubase | Steinberg |
| .OMG | O&O Software | Fichiers audio | O&O Image File | O&O DiskImage | O&O Software |
| .OMX | Ots Labs | Fichiers audio | OtsAV Media Library Information File | OtsAV DJ | Ots Labs |
| .OPUS | Open Source | Fichiers audio | Opus Audio File | Microsoft Windows Media Player | Microsoft Corporation |
| .ORC | Voyetra Turtle Beach | Fichiers audio | Voyetra Digital Orchestrator File | Digital Orchestrator | Voyetra Turtle Beach |
| .OSP | Jonathan Thomas | Fichiers audio | OpenShot Project File | OpenShot | Jonathan Thomas |
| .OTS | Apache Software Foundation | Fichiers audio | OpenDocument Spreadsheet Template | Apache OpenOffice | Apache Software Foundation |
| .OVE | Sonic Scores | Fichiers audio | Overture Musical Score | Overture | Sonic Scores |
| .OVW | Apple | Fichiers audio | Logic Pro Overview File | Logic Pro X | Apple |
| .P16 | HERE | Fichiers audio | HERE Maps For Android Map Data Package | HERE Maps | HERE |
| .PAC | NetScape | Fichiers audio | Proxy Auto-Config File | Internet Explorer | Microsoft Corporation |
| .PAT | Autodesk, Inc. | Fichiers audio | AutoCAD Hatch Pattern File | Autodesk AutoCAD | Autodesk, Inc. |
| .PBF | Paragon Software Group | Fichiers audio | Paragon Backup File | Paragon Backup & Recovery | Paragon Software Group |
| .PCA | Sony | Fichiers audio | Perfect Clarity Audio File | ACID Pro 7 | Magix Software GmbH |
| .PCG | Korg | Fichiers audio | Korg Instrument Bank File | Awave Studio | FMJ-Software |
| .PCH2 | Nord | Fichiers audio | Nord Modular G2 Patch | Modular G2 | Nord |
| .PCM | Various Developers | Fichiers audio | Pulse Code Modulation | MPlayer | The MPlayer Team |
| .PD | SAI | Fichiers audio | FlexiSIGN 5 Plotter Document | FlexiSIGN | SAI |
| .PEK | Adobe Systems Incorporated | Fichiers audio | Adobe Peak Waveform File | Adobe Premiere Pro CC | Adobe Systems Incorporated |
| .PEPPER | Pepper Computer | Fichiers audio | Pepper Keeper Shared Package File | Pepper Keeper | Pepper Computer |
| .PHO | Ucamco | Fichiers audio | Gerber Photoplot File | Altium Designer | Altium |
| .PHR | Adobe Systems Incorporated | Fichiers audio | RoboHelp Phrase List | Adobe RoboHelp | Adobe Systems Incorporated |
| .PHY | Autodesk, Inc. | Fichiers audio | 3ds Max Physique File | Autodesk 3ds Max | Autodesk, Inc. |
| .PJR | LabDV | Fichiers audio | DVDx Project File | DVDx | LabDV |
| .PK | Adobe Systems Incorporated | Fichiers audio | Audition Peak File | Adobe Audition | Adobe Systems Incorporated |
| .PKF | Adobe Systems Incorporated | Fichiers audio | Audition Peak File | Adobe Audition | Adobe Systems Incorporated |
| .PLA | SanDisk Corporation | Fichiers audio | Sansa Playlist File | Playlist Manager | Sprintbit Software |
| .PLM | FMJ-Software | Fichiers audio | DisorderTracker2 Module | Awave Studio | FMJ-Software |
| .PLS | Various Developers | Fichiers audio | Audio Playlist | VLC Media Player | VideoLAN |
| .PLY | MakeMusic, Inc. | Fichiers audio | Finale Playback File | Finale | MakeMusic, Inc. |
| .PNA | PhatNoise (Harman International) | Fichiers audio | PhatNoise Audio File | PhatNoise Music Manager | PhatNoise (Harman International) |
| .PNO | Microsoft Corporation | Fichiers audio | Windows 8 Piano Song | Microsoft Windows 8 | Microsoft Corporation |
| .PPC | Garmin | Fichiers audio | XMap Flight Plan Statistic File | XMap | Garmin |
| .PRG | Open Source | Fichiers audio | Program File | Notepad++ | Don Ho |
| .PSF | Adobe Systems Incorporated | Fichiers audio | Photoshop Proof Settings File | Adobe Photoshop Elements | Adobe Systems Incorporated |
| .PSI | SAPIEN Technologies | Fichiers audio | PrimalScript Online Help Shortcut | PrimalScript | SAPIEN Technologies |
| .PSM | Embarcadero Technologies | Fichiers audio | Turbo Pascal Symbol Table Of IDE | Turbo Pascal | Embarcadero Technologies |
| .PSY | Open Source | Fichiers audio | Psycle Song File | Psycle | Open Source |
| .PT3 | Harvard Graphics | Fichiers audio | Harvard Device Driver File | Harvard Graphics ChartXL | Harvard Graphics |
| .PTF | Sony | Fichiers audio | PSP Theme File | PSP Theme Toolbox | Unknown Developer |
| .PTM | Microsoft Corporation | Fichiers audio | MapPoint Map File | Microsoft MapPoint | Microsoft Corporation |
| .PTS | Avid Technology | Fichiers audio | Pro Tools Session | Avid Pro Tools | Avid Technology |
| .PTT | Avid Technology | Fichiers audio | Pro Tools Session Template | Avid Pro Tools | Avid Technology |
| .PTX | Adobe Systems Incorporated | Fichiers audio | PageMaker Template File | Adobe InDesign | Adobe Systems Incorporated |
| .PUI | Poster Software, LLC | Fichiers audio | Publish-iT Document | Publish-iT | Poster Software, LLC |
| .PVC | Panasonic Corporation | Fichiers audio | Panasonic VM1 Voice File | Panasonic Mini Player (VS2_VM1_Player.exe) | Panasonic Corporation |
| .PYA | Microsoft Corporation | Fichiers audio | Microsoft PlayReady DRM Audio File | Microsoft Windows Media Player | Microsoft Corporation |
| .PYV | Microsoft Corporation | Fichiers audio | Microsoft PlayReady Video | PlayReady | Microsoft Corporation |
| .Q2 | Nullsoft | Fichiers audio | Winamp Equalizer Auto-Load Presets File | Nullsoft Winamp | Nullsoft |
| .QAM | Omnis Software | Fichiers audio | Omnis Studio Audio Data | Omnis Studio | Omnis Software |
| .QCP | Qualcomm | Fichiers audio | PureVoice Audio File | QCP Converter | D.R. Software |
| .QSD | Quicken | Fichiers audio | Quicken Data | Intuit Quicken | Quicken |
| .QSF | Qualtrics | Fichiers audio | Qualtrics Survey File | Qualtrics Survey Solutions (online) | Qualtrics |
| .R | Open Source | Fichiers audio | R Script File | R | The R Foundation |
| .R1M | RealNetworks | Fichiers audio | RealOne Streaming Media File | RealPlayer Cloud | RealNetworks |
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