| .ETM | Etreppid Technologies, LLC | Fichiers audio | eTreppid Audio File | Unknown Software | Unknown Developer |
| .ETV | Open Source | Fichiers audio | eTreppid Audio Data | eTplayer | Open Source |
| .ETW | Enter Tech | Fichiers audio | Enter Tech Recorded Audio | Unknown Software | Unknown Developer |
| .EUPH | Nokia | Fichiers audio | Nokia File | Nokia phones | Nokia |
| .EVO | eZuce SRN | Fichiers audio | SeeVogh Player Video Recording | SeeVogh Player | eZuce SRN |
| .EVR | Qualcomm | Fichiers audio | Enhanced Variable Rate Audio File | RealPlayer | Realtime Technologies |
| .EXB | CAXA | Fichiers audio | CAXA Draft | IronCAD | IronCAD, LLC |
| .EXL | SysTools Solutions | Fichiers audio | Export Lister File | SysTools Export Notes | SysTools Solutions |
| .EXS | Apple | Fichiers audio | EXS Instrument | Apple Logic Pro | Apple |
| .F2R | Unknown Developer | Fichiers audio | Farandoyle Linear Module File | Awave Studio | FMJ-Software |
| .F32 | FMJ-Software | Fichiers audio | Raw 32-Bit Audio File | Unknown Software | Unknown Developer |
| .F3R | FMJ-Software | Fichiers audio | Farandoyle Blocked Module File | Awave Studio | FMJ-Software |
| .F4A | Adobe Systems Incorporated | Fichiers audio | Adobe Flash Protected Audio File | Adobe Flash Player | Adobe Systems Incorporated |
| .F4B | Adobe Systems Incorporated | Fichiers audio | Adobe Flash MP4 Audio eBook File | Adobe Flash Player | Adobe Systems Incorporated |
| .F64 | FMJ-Software | Fichiers audio | Raw 64-Bit Audio File | FMJ-Software Awave Audio | FMJ-Software |
| .FAR | Electronic Arts | Fichiers audio | The Sims Archive File | Dragon UnPACKer | Open Source |
| .FC | OpenText | Fichiers audio | FirstClass Settings File | OpenText FirstClass | OpenText |
| .FDA | Relic Entertainment | Fichiers audio | Dawn Of War Audio File | Relic Entertainment Dawn of War | Relic Entertainment |
| .FDP | UPEK | Fichiers audio | MySafe Encrypted Data | Protector Suite QL | UPEK |
| .FEV | Firelight Technologies | Fichiers audio | FMOD Audio Events File | Firelight Technologies FMOD Designer | Firelight Technologies |
| .FFF | Hasselblad | Fichiers audio | Hasselblad RAW Image | Microsoft Windows Photos | Microsoft Corporation |
| .FK | Flash-Integro LLC | Fichiers audio | Flash Streamed Media File | Adobe Flash Player | Adobe Systems Incorporated |
| .FLAC | Xiph.Org | Fichiers audio | Free Lossless Audio Codec File | Eltima Elmedia Player | Open Source |
| .FLM | Image-Line | Fichiers audio | FL Studio Mobile Song File | Image-Line FL Studio | Image-Line |
| .FLP | Image-Line | Fichiers audio | FL Studio Project File | LMMS | Open Source |
| .FNF | Lugert Verlag GmbH & Co. | Fichiers audio | Forte Notation File | Forte | Lugert Verlag GmbH & Co. |
| .FPA | MakeMusic, Inc. | Fichiers audio | Finale Performance Assessment File | Finale | MakeMusic, Inc. |
| .FPR | Hewlett-Packard | Fichiers audio | Audit Workbench Project | Fortify Static Code Analyzer | Hewlett-Packard |
| .FRG | Magix Software GmbH | Fichiers audio | Sound Forge Pro Project File | Sound Forge Pro | Magix Software GmbH |
| .FSB | AutoDesSys, Inc. | Fichiers audio | Form•Z Compiled Script | AutoDesSys formZ | AutoDesSys, Inc. |
| .FSC | ProFantasy Software Ltd | Fichiers audio | Campaign Cartographer File | Campaign Cartographer 3 | ProFantasy Software Ltd |
| .FTM | Interscape | Fichiers audio | FamiTracker Module | FamiTracker | jsr |
| .FUZ | Bethesda Softworks | Fichiers audio | Bethesda Softworks Voice File | Unfuzer | Bethesda Softworks |
| .FWV | MASTLabs, LLC | Fichiers audio | Fullwave Audio File | Fullwave | MASTLabs, LLC |
| .FXM | pmG Worldwide | Fichiers audio | MessiahStudio Motion File | pmG messiahStudio | pmG Worldwide |
| .FZB | Casio Computer Co., Ltd. | Fichiers audio | Casio FZ-1 Bank Dump | Awave Studio | FMJ-Software |
| .FZF | Casio Computer Co., Ltd. | Fichiers audio | Casio FZ-1 Full Dump | Awave Studio | FMJ-Software |
| .FZV | Unknown Developer | Fichiers audio | Casio FZ-1 Voice Dump | Awave Studio | FMJ-Software |
| .G36 | Open Source | Fichiers audio | Recomposer MIDI Sequence | TiMiDity++ | Open Source |
| .GDM | Open Source | Fichiers audio | Bells, Whistles, And Sound Boards Module | Awave Studio | FMJ-Software |
| .GIG | Piotr Fusik | Fichiers audio | Koala Painter Picture Image | Recoil | Piotr Fusik |
| .GIO | SourceForge | Fichiers audio | Adagio Score | Nyquist | SourceForge |
| .GM | GameMonkey | Fichiers audio | GameMonkey Script | Microsoft Notepad | Microsoft Corporation |
| .GP5 | Arobas Music | Fichiers audio | Guitar Pro 5 Tablature File | TuxGuitar | Julian Gabriel Casadesus and Others |
| .GPK | Steinberg | Fichiers audio | WaveLab Audio Peak File | WaveLab | Steinberg |
| .GPX | Unknown Developer | Fichiers audio | GPS Exchange File | Gedit | GNOME |
| .GRO | Open Source | Fichiers audio | Allegro MIDI File | Audacity | Open Source |
| .GSF | Nintendo | Fichiers audio | Game Boy Advance Sound File | Nullsoft Winamp | Nullsoft |
| .GVS | Open Source | Fichiers audio | GuitarVision Song File | GuitarVision Player | Open Source |
| .H0 | Magix Software GmbH | Fichiers audio | Movie Edit Pro Waveform Information File | MAGIX Movie Edit Pro | Magix Software GmbH |
| .HBB | Line 6 | Fichiers audio | Line 6 POD HD Edit Bundle | Line 6 POD Farm 2 | Line 6 |
| .HCO | Apple | Fichiers audio | Macintosh Sound Resource Fork File | macOS | Apple |
| .HDP | Microsoft Corporation | Fichiers audio | HD Photo File | Adobe Photoshop | Adobe Systems Incorporated |
| .HH | Microsoft Corporation | Fichiers audio | C++ Header File | Microsoft Notepad | Microsoft Corporation |
| .HIP | SideFX | Fichiers audio | Houdini Project File | Side Effects Houdini | SideFX |
| .HIT | Electronic Arts | Fichiers audio | The Sims Audio File | Electronic Arts SimCity 4 | Electronic Arts |
| .HMA | Sony | Fichiers audio | Sony HI-MD Audio File | Sony SonicStage | Sony |
| .HMI | Human Machine Interfaces | Fichiers audio | HMI Audio File | Nullsoft Winamp | Nullsoft |
| .HOT | Electronic Arts | Fichiers audio | The Sims Audio File | Electronic Arts SimCity 4 | Electronic Arts |
| .HSB | Steinberg | Fichiers audio | HALion Sound Bank File | Steinberg HALion | Steinberg |
| .HSC | Aspen Technology, Inc. | Fichiers audio | Aspen HYSYS Simulation File | Aspen HYSYS | Aspen Technology, Inc. |
| .HVL | Unknown Developer | Fichiers audio | Commodore Amiga HivelyTracker Audio Module | Audio Overload | Richard Bannister |
| .ICS | IronCAD, LLC | Fichiers audio | IronCAD 3D CAD Drawing File | IronCAD | IronCAD, LLC |
| .IDD | Adobe Systems Incorporated | Fichiers audio | Adobe InDesign For Mac Document | Adobe InDesign | Adobe Systems Incorporated |
| .IFF | Electronic Arts | Fichiers audio | Interchange File Format | IrfanView | Open Source |
| .IGP | Open Source | Fichiers audio | Igor Published Music Notation File | NoteHeads Igor Reader | Open Source |
| .IGR | Interscape | Fichiers audio | Igor Engraver File | Igor Engraver | Interscape |
| .IKX | iKlax Media | Fichiers audio | iKlax Creator Audio | iKlax Creator | iKlax Media |
| .ILB | Open Source | Fichiers audio | Scream Tracker Data | Scream Tracker 3 | Future Crew |
| .IMF | id Software | Fichiers audio | Id Music File | CocoModX | Open Source |
| .IMP | Lotus Software | Fichiers audio | Improv Spreadsheet File | Lotus 1-2-3 | IBM |
| .IMW | Unknown Developer | Fichiers audio | Imageware Surfacer 3D CAD Surface Geometry File | Unknown Software | Unknown Developer |
| .IM_ | Unknown Developer | Fichiers audio | Improve Compressed Audio File | Unknown Software | Unknown Developer |
| .INI | Microsoft Corporation | Fichiers audio | Windows Initialization File | Notepad++ | Don Ho |
| .INS | Open Source | Fichiers audio | LaTeX Installer Script | Microsoft Notepad | Microsoft Corporation |
| .ISS | Jordan Russell | Fichiers audio | Inno Setup Script | Microsoft Notepad | Microsoft Corporation |
| .IST | Flexera Software | Fichiers audio | InstallShield Project Template File | InstallShield | Flexera Software |
| .IT | Open Source | Fichiers audio | Impulse Tracker Module | ModPlug Player | Open Source |
| .ITI | Open Source | Fichiers audio | Impulse Tracker Instrument | CocoModX | Open Source |
| .ITS | Open Source | Fichiers audio | Impulse Tracker Sample | CocoModX | Open Source |
| .ITZ | Microsoft Corporation | Fichiers audio | Impulse Tracker Music Module | Impulse Tracker | Open Source |
| .JAM | Sierra Entertainment | Fichiers audio | Leisure Suit Larry Magna Cum Laude Archive File | Leisure Suit Larry: Magna Cum Laude | Sierra Entertainment |
| .JCB | Jason C. Brooke | Fichiers audio | CB-JCBrooke Song/Module | Unknown Software | Unknown Developer |
| .JCP | Xinox Software | Fichiers audio | JCreator Project File | JCreator | Xinox Software |
| .JDF | Adobe Systems Incorporated | Fichiers audio | Adobe Acrobat Job Definition File | Adobe Acrobat DC | Adobe Systems Incorporated |
| .JSPF | Oracle Corporation | Fichiers audio | Java Server Page Fragment | Adobe Dreamweaver | Adobe Systems Incorporated |
| .JWL | Roxio | Fichiers audio | Roxio Jewel Case File | Roxio Creator NXT Pro 5 | Roxio |
| .JXT | Interstellar Reasearch | Fichiers audio | Daqarta Extended Audio Data | Daqarta | Interstellar Reasearch |
| .K26 | Kurzweil Education | Fichiers audio | Kurzweil K2600 File | Awave Studio | FMJ-Software |
| .KAR | Various Developers | Fichiers audio | Karaoke MIDI File | KaraFun | Recisio |
| .KAT | Unknown Developer | Fichiers audio | Katorzer Music Composition | Katorzer | Unknown Developer |
| .KFN | Recisio | Fichiers audio | KaraFun Karaoke File | KaraFun | Recisio |
| .KFT | FMJ-Software | Fichiers audio | Korg T-series Wave Data | Awave Studio | FMJ-Software |
| .KIN | Cakewalk, Inc. | Fichiers audio | Kinetic Music Project | Cakewalk SONAR | Cakewalk, Inc. |
| .KIT | Bryan | Fichiers audio | CodeKit File | CodeKit | Bryan |
| .KMP | Korg | Fichiers audio | Korg Trinity/Triton Keymap File | Awave Studio | FMJ-Software |
| .KOZ | Chaoticom | Fichiers audio | Audiokoz Music File | Unknown Software | Unknown Developer |
| .KR1 | Kurzweil Education | Fichiers audio | Kurzweil 2000 Sample File | Awave Studio | FMJ-Software |
| .KRK | Interscape | Fichiers audio | Karaoke Music File | JBK Karaoke Player | Interscape |
| .KRX | Various Developers | Fichiers audio | Karaoke MIDI File | KaraFun | Recisio |
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