| .QC | Valve | Fichiers 3D | Half-Life Model Compiler Script File | Microsoft Notepad | Microsoft Corporation |
| .RAD | Reality Pump Studios | Fichiers 3D | Reality Adlib Tracker Module | Adlib Tracker II | Adlib Tracker II |
| .RAV | Nevrona Designs | Fichiers 3D | Rave Reports Project File | Rave Reports | Nevrona Designs |
| .RAW | Unknown Developer | Fichiers 3D | Raw Image Data File | MacPhun ColorStrokes | Macphun |
| .RAY | Craig Kolb | Fichiers 3D | Rayshade Image File | Rayshade | Craig Kolb |
| .RCS | RandomControl | Fichiers 3D | RandomControl Scene File | RandomControl Fryrender | RandomControl |
| .RDS | DAZ 3D | Fichiers 3D | Ray Dream Studio Scene File | DAZ Studio | DAZ 3D |
| .RFT | Autodesk, Inc. | Fichiers 3D | Revit Family Template File | AutoCAD Architecture | Autodesk, Inc. |
| .RIB | Pixar | Fichiers 3D | Renderman Interface Bytestream 3D Graphics File | RenderMan | Pixar |
| .RIG | Iterum, LLC | Fichiers 3D | vRigger Design File | Iterum vRigger | Iterum, LLC |
| .RS | Pierre-Emmanuel Gougelet | Fichiers 3D | Sun Raster Bitmap Image | XnView MP | XnSoft |
| .RVM | Eidos Interactive | Fichiers 3D | Revenant Game Archive | Revenant | Cinematix Studios, Inc. |
| .S | Unknown Developer | Fichiers 3D | Source Code File | Microsoft Notepad | Microsoft Corporation |
| .SAM | Microsoft Corporation | Fichiers 3D | LMHOSTS Sample File | Notepad++ | Don Ho |
| .SC4MODEL | Electronic Arts | Fichiers 3D | SimCity 4 Model File | Electronic Arts SimCity 4 | Electronic Arts |
| .SCAN | Unknown Developer | Fichiers 3D | Scan Data | Unknown Software | Unknown Developer |
| .SCENE | Fandom | Fichiers 3D | Antibody Level File | Hidden Temple Studios Antibody | Fandom |
| .SES | Adobe Systems Incorporated | Fichiers 3D | Audition Session File | Adobe Audition | Adobe Systems Incorporated |
| .SESSION | Dassault Systèmes | Fichiers 3D | CATIA 4 Session File | Adobe Acrobat DC | Adobe Systems Incorporated |
| .SG1 | Open Source | Fichiers 3D | Standford Graphics File | WinDS PRO | Open Source |
| .SGN | Signet Bureau | Fichiers 3D | Signet Bureau DRM File | SGN Viewer | Signet Bureau |
| .SH3D | eTeks | Fichiers 3D | Sweet Home 3D Design File | Sweet Home 3D | eTeks |
| .SHP | Autodesk, Inc. | Fichiers 3D | AutoCAD Shape File | Autodesk AutoCAD Ecscad | Autodesk, Inc. |
| .SI | Autodesk, Inc. | Fichiers 3D | Softimage Image File | Autodesk Softimage 2015 | Autodesk, Inc. |
| .SKL | Autodesk, Inc. | Fichiers 3D | Maya Skeleton File | Autodesk Maya | Autodesk, Inc. |
| .SKP | Trimble Inc. | Fichiers 3D | SketchUp Document | SketchUp | Trimble Inc. |
| .SM | Open Source | Fichiers 3D | StepMania Song File | StepMania | Open Source |
| .SMD | Valve | Fichiers 3D | Valve Studiomdl Data File | Microsoft Notepad | Microsoft Corporation |
| .SML | ESRI | Fichiers 3D | ARC/INFO Simple Macro Language File | ESRI ArcGIS for Desktop | ESRI (Environmental Systems Research Institute) |
| .SPH | National Institute of Standards and Technology (NIST) | Fichiers 3D | NIST SPHERE Audio File | SoX | Open Source |
| .SRF | NewTek | Fichiers 3D | LightWave Surface File | LightWave 3D | NewTek |
| .SRS | Microsoft Corporation | Fichiers 3D | Outlook Send/Receive Settings File | Microsoft Outlook | Microsoft Corporation |
| .SSB | Joshua Cannon Butcher | Fichiers 3D | Simply Safe Backup Archive | Simply Safe Backup | Joshua Cannon Butcher |
| .STC | Adobe Systems Incorporated | Fichiers 3D | Contribute Connection Key File | Adobe Contribute 6.5 | Adobe Systems Incorporated |
| .STEP | Unknown Developer | Fichiers 3D | STEP 3D Model | Autodesk Fusion 360 | Autodesk, Inc. |
| .STO | Ecru Software | Fichiers 3D | PRO100 3D Interior Design Project | Ecru Software PRO100 | Ecru Software |
| .STP | Unknown Developer | Fichiers 3D | STEP 3D CAD File | CATIA | Dassault Systèmes |
| .SVE | Simutrans Development Team | Fichiers 3D | Simutrans Saved Game | Simutrans | Simutrans Development Team |
| .T04 | Tobias Svensson | Fichiers 3D | Top 4 Compressed Data File | top 4 | Unknown Developer |
| .T3D | Epic Games | Fichiers 3D | Unreal Engine 3D Object File | Unreal Tournament | Epic Games |
| .TDDD | Impulse | Fichiers 3D | Imagine Object File Format | Impulse Imagine | Impulse |
| .TDIM | Unknown Developer | Fichiers 3D | Digital F/X Image Format | XnView MP | XnSoft |
| .TER | Planetside Software | Fichiers 3D | Terragen Terrain File | Planetside Software Terragen | Planetside Software |
| .TGM | Open Source | Fichiers 3D | Nem's Mega 3D Terrain Generator | Nem's Mega 3D Terrain Generator | Open Source |
| .THL | Individual Software Inc. | Fichiers 3D | Total 3D Home Design File | Total 3D Home Design Deluxe | Individual Software Inc. |
| .THUMBDATA3 | Google | Fichiers 3D | Google Android Thumbnail Database | Google Android | Google |
| .THUMBDATA5 | Google | Fichiers 3D | Google Android Thumbnail Database | Google Android | Google |
| .TIN | Bentley Systems | Fichiers 3D | Bentley GEOPAK Environmental Modeling Systems Data | GEOPAK Civil Engineering Suite | Bentley Systems |
| .TMD | SoftMaker Software | Fichiers 3D | TextMaker Document | Softmaker Office | SoftMaker Software |
| .TME | DAZ 3D | Fichiers 3D | Bryce Time File | DAZ 3D Bryce | DAZ 3D |
| .TML | Odetics Broadcast | Fichiers 3D | AIRO Timeline File Format | AIRO | Odetics Broadcast |
| .TMO | Yu Higuchi | Fichiers 3D | 3DCG Animation And Pose File | MikuMikuDance | Yu Higuchi |
| .TMP | Mozilla | Fichiers 3D | General Temporary File | Internet Explorer | Microsoft Corporation |
| .TNL | Unknown Developer | Fichiers 3D | Thumbnail Image Format | Unknown Software | Unknown Developer |
| .TOP | KTH Royal Institute of Technology | Fichiers 3D | Gromacs Topology File | Gromacs | KTH Royal Institute of Technology |
| .TOTAL COMMANDER BUTTON BAR SETTINGS | Interscape | Fichiers 3D | Total Commander Button Bar Settings | Total Commander | Ghisler Software GmbH |
| .TPS | TiePie engineering | Fichiers 3D | Multi Channel Measurement File | Multi Channel | TiePie engineering |
| .TRI | Singular Inversions | Fichiers 3D | FaceGen Polygonal Model File | The Elder Scrolls IV: Oblivion | Bethesda Softworks |
| .TRU | Original Basic | Fichiers 3D | True Basic Source | True Basic Bronze Edition | Original Basic |
| .TSO | Siemens AG | Fichiers 3D | NX2 File 3D Faceted Spacial Volume Data | Siemens PLM NX | Siemens PLM Software |
| .TVP | NVIDIA | Fichiers 3D | NVIDIA Graphic Card Update File | NVIDIA Graphics Driver | NVIDIA |
| .U3D | 3D Industry Forum | Fichiers 3D | Universal 3D File | Adobe Acrobat DC | Adobe Systems Incorporated |
| .UMS | Open Source | Fichiers 3D | Dragon UnPACKer Version 5 Archive File | Dragon UnPACKer | Open Source |
| .V2D | Archway Systems | Fichiers 3D | VersaCAD File | Archway Systems VersaCAD | Archway Systems |
| .V2L | Texas Instruments, Inc. | Fichiers 3D | TI Voyage 200 List | Voyage 200 | Texas Instruments, Inc. |
| .V3D | Realmware Corporation | Fichiers 3D | Visual3D.NET Data File | Visual3D.NET | Realmware Corporation |
| .V3O | Sixteen Tons Entertainment | Fichiers 3D | Emergency 3 And 4 Model File | Zanoza ZModeler | Zanoza Software |
| .V3V | Vectric Ltd. | Fichiers 3D | Vector Art 3D Model File | Vector Art 3D Viewer | Vectric Ltd. |
| .VAC | Ipswitch, Inc. | Fichiers 3D | IMail Server Vacation Message File | Ipswitch IMail Server | Ipswitch, Inc. |
| .VBL | Asphalt Research Consortium | Fichiers 3D | 3DMove 3D Geological Model File | 3DMove | Asphalt Research Consortium |
| .VEG | Magix Software GmbH | Fichiers 3D | VEGAS Video Project | MAGIX Vegas | Magix Software GmbH |
| .VIS | Microsoft Corporation | Fichiers 3D | Visibility Image File | Microsoft Flight Simulator 2004 | Microsoft Corporation |
| .VLS | AIT | Fichiers 3D | Visual Localize Script | Visual Localize | AIT |
| .VMD | Open Source | Fichiers 3D | Covox Raw Sample | Virtual Sound Blaster | Creative Technology Ltd. |
| .VMO | Siemens AG | Fichiers 3D | Siemens Voice Memo File | Siemens Mobile Phones | Siemens AG |
| .VOB | The DVD Forum | Fichiers 3D | DVD Video Object File | CyberLink PowerDVD | CyberLink |
| .VOX | Ken Silverman | Fichiers 3D | Voxlap Voxel Model File | MagicaVoxel | Interscape |
| .VP | Accellera Systems Initiative | Fichiers 3D | Verilog Encrypted Source Code File | Xilinx ISE WebPACK | Xilinx, Inc. |
| .VPD | Yu Higuchi | Fichiers 3D | MikuMikuDance Vocaloid Pose Data File | MikuMikuDance | Yu Higuchi |
| .VRL | Unknown Developer | Fichiers 3D | VRML World | IMSI TurboCAD Deluxe | Redway3d and others |
| .VS | OpenGL | Fichiers 3D | Vertex Shader File | Microsoft DirectX SDK | Microsoft Corporation |
| .VSO | Microsoft Corporation | Fichiers 3D | Compiled Vertex Shader File | Microsoft DirectX SDK | Microsoft Corporation |
| .VTX | Richard Bannister | Fichiers 3D | VTX Chiptune File | Audio Overload | Richard Bannister |
| .VUE | E-on Software, Inc. | Fichiers 3D | Vue Scene File | E-on Vue | E-on Software, Inc. |
| .VVD | Konica Minolta | Fichiers 3D | Vivid 3D Scanner Element File | Rapidform Explorer (Geomagic Verify Viewer) | Rapidform, Inc. |
| .W3D | Adobe Systems Incorporated | Fichiers 3D | Adobe Shockwave 3D File | Adobe Director | Adobe Systems Incorporated |
| .WINGS | Open Source | Fichiers 3D | Wings 3D File | Wings 3D | Open Source |
| .WR1 | IBM | Fichiers 3D | Lotus Symphony Spreadsheet | IBM Lotus Symphony | IBM |
| .WRL | Unknown Developer | Fichiers 3D | VRML World | IMSI TurboCAD Deluxe | Redway3d and others |
| .WRP | 3D Systems | Fichiers 3D | Geomagic 3D Wrap File | Geomagic Studio | 3D Systems |
| .WRZ | Parallel Graphics | Fichiers 3D | Compressed VRML World File | TurboCAD | IMSI/Design, LLC |
| .WWI | DIGITAL Soft | Fichiers 3D | WinWein Interchange Format Data | WinWein | DIGITAL Soft |
| .X | Microsoft Corporation | Fichiers 3D | DirectX Model File | Microsoft DirectX SDK | Microsoft Corporation |
| .X3D | Microsoft Corporation | Fichiers 3D | Compiled Vertex Shader File | Microsoft DirectX SDK | Microsoft Corporation |
| .X3DB | Web3D Consortium | Fichiers 3D | X3D Binary Format | X3D | Web3D Consortium |
| .XAF | Autodesk, Inc. | Fichiers 3D | 3ds Max XML Animation File | IMVU | IMVU, Inc. |
| .XDE | Unknown Developer | Fichiers 3D | Tgif-3.0 File | Unknown Software | Unknown Developer |
| .XDK | Virtual Media Republicorp | Fichiers 3D | XML Development Kit Project | XML Development Kit | Virtual Media Republicorp |
| .XFR | TIBCO Software Inc | Fichiers 3D | iProcess Process Definition File | TIBCO iProcess Suite | Xmarter |
| .XMF | Open Source | Fichiers 3D | Cal3D XML Mesh File | Cal3DViewer | Open Source |
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