| .CDF | Wolfram Research | Fichiers de mise en page | Computable Document Format File | Wolfram Research CDF Player | Wolfram Research |
| .FITS | Open Source | Fichiers Raster Image | Flexible Image Transport System File | Wolfram Research Mathematica | Wolfram Research |
| .M | MathWorks | Fichiers de développeurs | MATLAB Source Code File | Wolfram Research Mathematica | Wolfram Research |
| .MA | Autodesk, Inc. | Fichiers 3D | Maya Project File | Wolfram Research Mathematica | Wolfram Research |
| .MDB | Microsoft Corporation | Fichiers de base de données | Microsoft Access Database | Wolfram Research Mathematica | Wolfram Research |
| .MM | Kodak | Fichiers de données | Kodak EasyShare Thumbnail Cache File | Wolfram Research Mathematica | Wolfram Research |
| .MX | Wolfram Research | Fichiers de données | Mathematica Serialized Package File | Wolfram Research Mathematica | Wolfram Research |
| .NB | Wolfram Research | Fichiers de feuille de calcul | Mathematica Notebook | Wolfram Research Mathematica | Wolfram Research |
| .NBP | Wolfram Research | Fichiers de données | Mathematica Player Notebook File | Wolfram Research Mathematica | Wolfram Research |
| .PIXAR | Pixar | Fichiers Raster Image | Pixar Image File | Wolfram Research Mathematica | Wolfram Research |
| .PLY | MakeMusic, Inc. | Fichiers audio | Finale Playback File | Wolfram Research Mathematica | Wolfram Research |
| .PNM | XnSoft | Fichiers Raster Image | Portable Any Map Image | Wolfram Research Mathematica | Wolfram Research |
| .PXR | Pixar | Fichiers Raster Image | Pixar Image File | Wolfram Research Mathematica | Wolfram Research |
| .TGF | Unknown Developer | Fichiers de données | Trivial Graph Format File | Wolfram Research Mathematica | Wolfram Research |
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