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| Extension | File Type Developer | File Category | File Type Description | Primary Software | Primary Software Developer |
|---|---|---|---|---|---|
| .U2 | IBM | Developer Files | Telelogic Tau UML Model File | Rational Tau | IBM |
| .U2P | IBM | Developer Files | Telelogic Tau UML Program Text File | Rational Tau | IBM |
| .UAE | Interscape | Developer Files | WinUAE Configuration Data | WinUAE | Interscape |
| .UCLS | ObjectAid | Developer Files | ObjectAid UML Explorer Class Diagram | ObjectAid UML Explorer | ObjectAid |
| .UDD | Oleh Yuschuk | Developer Files | OllyDbg Module Information | OllyDbg | Oleh Yuschuk |
| .UDF | Open Source | Developer Files | Universal Disk Format Image File | 7-Zip | Igor Pavlov |
| .UI | Digia Oyj | Developer Files | User Interface File | Qt SDK | The Qt Company |
| .UIH | Geoworks Ensemble | Developer Files | Geoworks UI Compiler Espire Header | GEOS | GEOS |
| .UML | Visual Object Modelers | Developer Files | UML Data Object Model | Eclipse IDE for Java Developers | The Eclipse Foundation |
| .UMLCLASS | The Eclipse Foundation | Developer Files | UML Class Model | Eclipse IDE for Java Developers | The Eclipse Foundation |
| .UNX | Unknown Developer | Developer Files | Unknown Apple II File. (found On Golden Orchard Apple II CD Rom) | Atom | GitHub, Inc. |
| .USE | Unknown Developer | Developer Files | Log File | Microsoft Notepad | Microsoft Corporation |
| .USI | Sublime HQ Pty Ltd | Developer Files | UsiXML UI Description Data | Sublime Text | Sublime HQ Pty Ltd |
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