| .NV | Q.W.Page Associates Inc | Database Files | NewViews Database File | Q.W. Page NewViews 2 | Q.W.Page Associates Inc |
| .NV2 | Q.W.Page Associates Inc | Database Files | NewViews 2 Database File | Q.W. Page NewViews 2 | Q.W.Page Associates Inc |
| .NX1 | NexusDB Pty | Database Files | NexusDB File | NexusDB | NexusDB Pty |
| .NX2 | NexusDB Pty | Database Files | NexusDB Database File | NexusDB | NexusDB Pty |
| .NYF | Wjj Software | Database Files | MyBase Database File | Wjj Software myBase | Wjj Software |
| .OD4 | Omnis Software | Database Files | Omnis5 Database File | Omnis Studio | Omnis Software |
| .OD9 | Omnis Software | Database Files | Omnis5 Database File | Omnis Studio | Omnis Software |
| .ODB | Various Developers | Database Files | OpenDocument Database | Apache OpenOffice | Apache Software Foundation |
| .OPT | LexisNexis | Database Files | Concordance Database File | LexisNexis Concordance | LexisNexis |
| .OQY | Microsoft Corporation | Database Files | Excel OLAP Query File | Microsoft Excel | Microsoft Corporation |
| .ORA | Unknown Developer | Database Files | OpenRaster Image File | GIMP | The GIMP Development Team |
| .ORD | OMAX Corporation | Database Files | OMAX Routed Data | Unknown Software | Unknown Developer |
| .OTQ | One MarketData, LLC | Database Files | OneTick Query File | OneTick | One MarketData, LLC |
| .OWC | OutWit Technologies | Database Files | OutWit Catch Database | Mozilla Firefox | Mozilla |
| .OXB | Olapxsoftware | Database Files | OlapX Report Portfolio Data File | OlapX Application | Olapxsoftware |
| .OXC | Olapxsoftware | Database Files | OlapX | OlapX Application | Olapxsoftware |
| .PAG | Microsoft Corporation | Database Files | Visual Basic Property PAGe File | Microsoft Visual Basic | Microsoft Corporation |
| .PAN | ProVUE Development | Database Files | Panorama Database File | ProVUE Development Panorama | ProVUE Development |
| .PBD | EaseUS | Database Files | EaseUS Todo Backup Backup File | EaseUS Todo Backup | EaseUS |
| .PCA | Sony | Database Files | Perfect Clarity Audio File | ACID Pro 7 | Magix Software GmbH |
| .PDM | Sybase, Inc | Database Files | PowerDesigner Database File | Sybase PowerDesigner | SAP |
| .PDT | Microsoft Corporation | Database Files | InkWriter Note Taker Template File | Windows Mobile | Microsoft Corporation |
| .PHM | Pro Home Manager, LLC | Database Files | Pro Home Manager Data File | Pro Home Manager | Pro Home Manager, LLC |
| .PLD | Oracle Corporation | Database Files | Oracle Binary Module Text Form | Oracle Database | Oracle Corporation |
| .PNZ | ProVUE Development | Database Files | Panorama Database Set | ProVUE Development Panorama | ProVUE Development |
| .PRK | LucasArts Entertainment Company, LLC | Database Files | Thrillville Park File | Thrillville | Frontier Developments plc |
| .PSAFE3 | Open Source | Database Files | Password Safe Database | Password Safe | Open Source |
| .PW | Pointwise, Inc. | Database Files | Pointwise Database File | Pointwise | Pointwise, Inc. |
| .QBQUERY | MySQL AB | Database Files | MySQL Query Browser Saved SQL Query Command Data | MySQL Query Browser | MySQL AB |
| .QD0 | Omnis Software | Database Files | Omnis Quartz Segment 10 Data File | Omnis Studio | Omnis Software |
| .QD1 | Omnis Software | Database Files | Omnis Quartz Segment 1 Data File | Omnis Studio | Omnis Software |
| .QD2 | Omnis Software | Database Files | Omnis Quartz Segment 2 Data File | Omnis Studio | Omnis Software |
| .QD5 | Omnis Software | Database Files | Omnis Quartz Segment 5 Data File | Omnis Studio | Omnis Software |
| .QD6 | Omnis Software | Database Files | Omnis Quartz Segment 6 Data File | Omnis Studio | Omnis Software |
| .QD8 | Omnis Software | Database Files | Omnis Quartz Segment 8 Data File | Omnis Studio | Omnis Software |
| .QDC | Quotalys Ltd. | Database Files | Quick-Devis Database | Quick-Devis Database | Quotalys Ltd. |
| .QMF | IBM | Database Files | IBM Lotus Approach Database Query | Lotus Approach | IBM |
| .QRY | Oracle Corporation | Database Files | Query File | Microsoft SQL Server | Microsoft Corporation |
| .QVD | Qlik | Database Files | QlikView Data File | QlikTech International QlikView | Qlik |
| .QVF | Qlik | Database Files | QlikView Data File | QlikTech International QlikView | Qlik |
| .R2K | BTM Innovation Pty | Database Files | Repertoire 2000 Music Database | Repertoire 2000 | BTM Innovation Pty |
| .RBF | Microsoft Corporation | Database Files | Windows Installer Rollback File | Windows Installer | Microsoft Corporation |
| .REX | Propellerhead | Database Files | ReCycle Loop File | Avid Pro Tools | Avid Technology |
| .RFG | Raddon Financial Group | Database Files | RFG Integrator System Database | Integrator | Fiserv, Inc. |
| .RFH | Raddon Financial Group | Database Files | RFG Integrator Householding Database | Integrator | Fiserv, Inc. |
| .RFL | Propellerhead | Database Files | Reason ReFill Sound Bank File | Reason | Propellerhead |
| .RIN | Protronics | Database Files | Retrieve 4GL Database Index | Retrieve 4GL | Protronics |
| .RMW | ALD | Database Files | RAM Commander Database File | RAM Commander | ALD |
| .ROD | RIB Software | Database Files | RIB Office Database File | RIB office | RIB Software |
| .RPC | Synthrone | Database Files | Rich Page Content Document | Synthrone Crafter | Synthrone |
| .RPD | RIB Software | Database Files | RIB Project Database File | iTWO | RIB Software |
| .RSD | Rosetta Stone | Database Files | Rosetta Stone Data File | Rosetta Stone Language Learning | Rosetta Stone |
| .RXD | Attachmate (Micro Focus) | Database Files | Attachmate Reflection X Manager Definition Data File | Attachmate Reflection | Attachmate (Micro Focus) |
| .RXH | Borland | Database Files | Reflex Database Help File | Borland Reflex | Borland |
| .SAS7BDAT | SAS Institute Inc. | Database Files | SAS Data Set File | SAS | SAS Institute Inc. |
| .SBF | Google | Database Files | Android System File | Google Android | Google |
| .SCX | RIX SoftWorks, Inc. | Database Files | ColoRIX Bitmap Graphic File | XnView MP | XnSoft |
| .SD2 | Avid Technology | Database Files | Sound Designer II File | Apple iTunes | Apple |
| .SDF | Microsoft Corporation | Database Files | SQL Server Compact Database File | Microsoft Visual Studio | Microsoft Corporation |
| .SDI | Intuit, Inc. | Database Files | QuickBooks Data File | Intuit QuickBooks Pro | Intuit, Inc. |
| .SDS | Oracle Corporation | Database Files | OpenOffice.org Chart | Apache OpenOffice | Apache Software Foundation |
| .SF1 | The U.S. Census Bureau | Database Files | 2010 Census Summary File 1 | Microsoft Access | Microsoft Corporation |
| .SG3 | SourceForge | Database Files | ChessDB Game File | ChessDB | Interscape |
| .SIS | Valve | Database Files | Steam Game Backup Information File | Steam | Valve |
| .SKC | Borland | Database Files | SideKick For Windows Database File | Borland SideKick | Borland |
| .SLF | Symantec Corporation | Database Files | Symantec License File | Symantec Ghost Solution Suite | Symantec Corporation |
| .SQDB | TedCo Software, LLC | Database Files | SpellQuizzer Database File | SpellQuizzer | TedCo Software, LLC |
| .SQL | Various Developers | Database Files | Structured Query Language Data File | Microsoft Notepad | Microsoft Corporation |
| .SQLITE | Dwayne Richard Hipp | Database Files | SQLite Database File | SQLite | Dwayne Richard Hipp |
| .SQLITEDB | Dwayne Richard Hipp | Database Files | SQLite Database | SQLite | Dwayne Richard Hipp |
| .SR1 | SIR Pty Ltd. | Database Files | SIR Database | SIR/XS | SIR Pty Ltd. |
| .SR3 | SIR Pty Ltd. | Database Files | SIR Database | SIR/XS | SIR Pty Ltd. |
| .SR4 | SIR Pty Ltd. | Database Files | SIR Database | SIR/XS | SIR Pty Ltd. |
| .SSO | Interscape | Database Files | ChessDB Search Options Data | ChessDB | Interscape |
| .SV2 | SAS Institute Inc. | Database Files | SAS View | Base SAS | SAS Institute Inc. |
| .SV7 | Nintendo | Database Files | Saved Game File | No Cash GBA (No$GBA) | Martin Korth |
| .TBM | Nabi Studios | Database Files | Toribash Mod File | Toribash | Nabi Studios |
| .TE | RM Education | Database Files | Textease CT Database File | Textease Studio | RM Education |
| .TFR | LucasArts Entertainment Company, LLC | Database Files | TIE Fighter Pilot File | Star Wars: TIE Fighter | LucasArts Entertainment Company, LLC |
| .TMD | SoftMaker Software | Database Files | TextMaker Document | Softmaker Office | SoftMaker Software |
| .TMDB | Interfathom | Database Files | TaskMerlin Database File | TaskMerlin | Interfathom |
| .TMZ | The MediGraph Team | Database Files | Medigraph Compressed Database File | Medigraph | The MediGraph Team |
| .TOM | Aptora | Database Files | Total Office Manager Accounting Data | Total Office Manager | Aptora |
| .TPS | TiePie engineering | Database Files | Multi Channel Measurement File | Multi Channel | TiePie engineering |
| .TRC | Microsoft Corporation | Database Files | SQL Server Trace File | Microsoft SQL Server | Microsoft Corporation |
| .TRM | Oracle Corporation | Database Files | Oracle Trace Map File | Oracle Database | Oracle Corporation |
| .UDF | Open Source | Database Files | Universal Disk Format Image File | 7-Zip | Igor Pavlov |
| .UFSD | SysDevSoftware | Database Files | RAW Recovery Signatures Database File | SysDevSoftware UFS Explorer | SysDevSoftware |
| .URD | Kinook Software, Inc. | Database Files | Ultra Recall Database File | Ultra Recall | Kinook Software, Inc. |
| .USR | FileMaker Inc. | Database Files | FileMaker Pro Database File | FileMaker Pro | FileMaker Inc. |
| .UXD | Terria Development | Database Files | URLBase URL Database | URLBase | Terria Development |
| .VAS | EduFlex | Database Files | VirtualAssessor Diagnostic Scenario Database | VirtualAssessor | EduFlex |
| .VDF | Valve | Database Files | Valve Data File | Microsoft Notepad | Microsoft Corporation |
| .VDX | Microsoft Corporation | Database Files | Visio Drawing XML File | OmniGraffle | The Omni Group |
| .VIS | Microsoft Corporation | Database Files | Visibility Image File | Microsoft Flight Simulator 2004 | Microsoft Corporation |
| .VIW | Microsoft Corporation | Database Files | Microsoft SQL Server View Script File | Microsoft SQL Server | Microsoft Corporation |
| .VL | Tailwag Software | Database Files | Visual Labels Project | Visual Labels | Tailwag Software |
| .VPD | Yu Higuchi | Database Files | MikuMikuDance Vocaloid Pose Data File | MikuMikuDance | Yu Higuchi |
| .VPDB | VIP Quality Software | Database Files | VIP Organizer Database | VIP Organizer | VIP Quality Software |
| .VPW | Wheat Stone | Database Files | VoxPro Database File | VoxPro | Wheat Stone |
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