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| Extension | File Type Developer | File Category | File Type Description | Primary Software | Primary Software Developer |
|---|---|---|---|---|---|
| .SEV | Open Source | Data Files | SevenUp Picture | ZX-Paintbrush | Open Source |
| .SF | Institut de Recherche et de Coordination Acoustique/Musique (IRCAM) | Data Files | IRCAM Sound File | Awave Studio | FMJ-Software |
| .SF3 | Statpoint Technologies, Inc. | Data Files | STATGRAPHICS Data File | STATGRAPHICS | Statpoint Technologies, Inc. |
| .SFA | Sony | Data Files | Sony Sound Forge File | Sound Forge Pro | Magix Software GmbH |
| .SFF | Elecbyte | Data Files | M.U.G.E.N. Sprite File | Elecbyte M.U.G.E.N | Elecbyte |
| .SFM | Samsung Electronics | Data Files | S Memo Data Cache | S Memo | Samsung Electronics |
| .SFS | Open Source | Data Files | Squashfs File Archive | 7-Zip | Igor Pavlov |
| .SG | Unknown Developer | Data Files | SG-1000 Game ROM File | Kega Fusion | Steve Snake |
| .SGB | Relic Entertainment | Data Files | Dawn Of War Map File | Relic Entertainment Dawn of War | Relic Entertainment |
| .SGCPO | Stenograph | Data Files | Case CATalyst File | Case CATalyst | Stenograph |
| .SGML | Corel | Data Files | Standard Generalized Markup Language File | Corel WordPerfect X8 | Corel |
| .SGN | Signet Bureau | Data Files | Signet Bureau DRM File | SGN Viewer | Signet Bureau |
| .SGNGL | Stenograph | Data Files | Case CATalyst File | Case CATalyst | Stenograph |
| .SGO | Volkswagen | Data Files | ECU Update | Engine Control Unit (ECU) | Volkswagen |
| .SGR | Electronic Arts | Data Files | SimCity 4 Graphics Rules File | Electronic Arts SimCity 4 | Electronic Arts |
| .SGX | Lahey Computer Systems, Inc. | Data Files | Lahey Fortran Help Index File | SView5 | Andreas R Kleinert |
| .SGY | Open Source | Data Files | SEG-Y Seismic Data File | Segpy | Open Source |
| .SH3 | Software Publishing Corporation (SPC) | Data Files | Harvard Graphics 3.0 Presentation File | Harvard Graphics Presentation Software | Software Publishing Corporation (SPC) |
| .SHAPE | Dia Development Team | Data Files | Dia Diagram Editor Shape File | Dia Diagram Editor | Dia Development Team |
| .SHC | Adobe Systems Incorporated | Data Files | Adobe Photoshop Contours File | Adobe Photoshop CC | Adobe Systems Incorporated |
| .SHEET | Dia Development Team | Data Files | Dia Sheet File | Dia Diagram Editor | Dia Development Team |
| .SHELL | Apple | Data Files | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .SHF | Symantec Corporation | Data Files | Pretty Good Privacy (PGP) Share | Pretty Good Privacy (PGP) | Symantec Corporation |
| .SHM | Corel | Data Files | Corel WordPerfect Shell Library File | Corel WordPerfect | Corel |
| .SHOP | Apple | Data Files | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .SHOW | Hancom, Inc. | Data Files | Thinkfree Office NEO Presentation Document | Thinkfree Office NEO | Hancom, Inc. |
| .SHU | FormatBlue Software | Data Files | SnippetHub Export/Import File | SnippetHub | FormatBlue Software |
| .SHW | Corel | Data Files | Corel Presentations Slide Show | Corel Presentations X8 | Corel |
| .SHX | Autodesk, Inc. | Data Files | AutoCAD Compiled Shape File | Autodesk AutoCAD Civil 3D | Autodesk, Inc. |
| .SHZ | Paracodex | Data Files | Ximage File | Ximage | Paracodex |
| .SI3 | Interscape | Data Files | ChessDB Index File | ChessDB | Interscape |
| .SIC | Intuit, Inc. | Data Files | Quicken 2002 Financial Data | Intuit Quicken | Quicken |
| .SIG | Unknown Developer | Data Files | Signature File | Microsoft Outlook Express | Microsoft Corporation |
| .SIGNUP | Unknown Developer | Data Files | Unknown Apple II File. (found On Golden Orchard Apple II CD Rom) | Atom | GitHub, Inc. |
| .SIM | Valve | Data Files | Steam Game Backup Information File | Steam | Valve |
| .SKL | Autodesk, Inc. | Data Files | Maya Skeleton File | Autodesk Maya | Autodesk, Inc. |
| .SKS | Eltima Software | Data Files | Show.kit Template | Show.kit | Eltima Software |
| .SKT | Intermorphic | Data Files | SSEYO Koan Data | Noatikl | Intermorphic |
| .SKV | Microsoft Corporation | Data Files | Semicolon Separated Values File | Microsoft Excel | Microsoft Corporation |
| .SKW | Borland | Data Files | SideKick Calendar Data | Borland SideKick | Borland |
| .SKX | Microsoft Corporation | Data Files | XLANG Schedule File | BizTalk Server | Microsoft Corporation |
| .SL | SourceForge | Data Files | Unix Software License File | Vi | SourceForge |
| .SLAP | Apple | Data Files | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .SLDX | Microsoft Corporation | Data Files | Microsoft PowerPoint Open XML Slide | Microsoft PowerPoint | Microsoft Corporation |
| .SLE | Sisulizer | Data Files | Sisulizer Package File | Sisulizer | Sisulizer |
| .SLF | Symantec Corporation | Data Files | Symantec License File | Symantec Ghost Solution Suite | Symantec Corporation |
| .SLG | Dionex Corporation | Data Files | Chromeleon Audit Trail Data | Chromeleon | Dionex Corporation |
| .SLI | MR Software | Data Files | OMSI Spline Configuration File | OMSI 2 | MR Software |
| .SLIP | Embarcadero Technologies | Data Files | CodeGear License Data | JBuilder | Embarcadero Technologies |
| .SLK | Microsoft Corporation | Data Files | Symbolic Link File | Microsoft Excel | Microsoft Corporation |
| .SLL | ShopTalk Systems | Data Files | Static Link Library | Shoptalk Systems Just BASIC | ShopTalk Systems |
| .SLN | Microsoft Corporation | Data Files | Microsoft Visual Studio Solution File | VSoft Technologies FinalBuilder | VSoft Technologies |
| .SLP | Magix Software GmbH | Data Files | SpectraLayers Pro Project | SpectraLayers Pro | Magix Software GmbH |
| .SLT | Mozilla | Data Files | Mozilla User Profile Folder | Mozilla Firefox | Mozilla |
| .SLU | Pervasive Software | Data Files | Business Integrator Upgrade License Data | Pervasive Business Integrator | Pervasive Software |
| .SLW | Settler Computer Technologies | Data Files | Settler LITE Data File | Settler LITE | Settler Computer Technologies |
| .SLX | MathWorks | Data Files | MathWorks Simulink Model | Simulink | MathWorks |
| .SM | Open Source | Data Files | StepMania Song File | StepMania | Open Source |
| .SM+ | DataCAD LLC | Data Files | DataCAD Plus Symbol File | DataCAD | DataCAD LLC |
| .SMA | Don Ho | Data Files | C/C++ Source Code File | MacroMates TextMate | MacroMates |
| .SMART2 | Apple | Data Files | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .SMB | Autodesk, Inc. | Data Files | Autodesk Symbol Library | Autodesk AutoCAD Ecscad | Autodesk, Inc. |
| .SMCL | StataCorp | Data Files | Stata Log | Stata | StataCorp |
| .SMDF | Cloud Peak Software | Data Files | Surface Magic Design | WaveMaker | WaveMaker, Inc. |
| .SML2 | Apple | Data Files | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .SMM | Samsung Electronics | Data Files | Samsung Memo File | Samsung Kies | Samsung Electronics |
| .SMN | Unknown Developer | Data Files | ParaGraph WorkScript Data | Unknown Software | Unknown Developer |
| .SMP | MakeMusic, Inc. | Data Files | SmartMusic Performance File | SmartMusic | MakeMusic, Inc. |
| .SMS | Sega | Data Files | Sega Master System ROM | Kega Fusion | Steve Snake |
| .SMT | Intuit, Inc. | Data Files | QuickBooks Data File | Intuit QuickBooks Pro | Intuit, Inc. |
| .SMU | Tomas Pettersson | Data Files | Simple Musical Score File | Musagi | Tomas Pettersson |
| .SMV | Smith Micro Software | Data Files | VideoLink Mail Video File | Smith Micro Videolink Pro | Smith Micro Software |
| .SMX | MakeMusic, Inc. | Data Files | SmartMusic XML File | SmartMusic | MakeMusic, Inc. |
| .SMZ | Open Source | Data Files | SMath Studio Compressed Document | SMath Studio | Open Source |
| .SN3 | Samsung Electronics | Data Files | Samsung Kies 2 Backup | Samsung Kies | Samsung Electronics |
| .SNAG | TechSmith | Data Files | SnagIt Capture File | Snagit | TechSmith |
| .SNAP | Erik Kunze | Data Files | ZX Spectrum Emulator Mirage Microdrive Snapshot | XZX-Pro | Erik Kunze |
| .SNAPSHOT | VMware | Data Files | VMware ThinApp Snapshot File | VMware ThinApp 5 Suite | VMware |
| .SNE | Biognosys | Data Files | Spectronaut Experiments Data | Spectronaut | Biognosys |
| .SNF | The Open Group | Data Files | UNIX Font | Unix | AT&T Labs |
| .SNIFFER | Unknown Developer | Data Files | Sniffer Trace File | Unknown Software | Unknown Developer |
| .SNIP | Microsoft Corporation | Data Files | Microsoft Windows Snipping Tool Data File | Snipping Tool | Microsoft Corporation |
| .SNL | Interscape | Data Files | Egrid32 Form Snippet | EGrid Form Designer | Interscape |
| .SOA | Sage | Data Files | Sage MAS 90 Accounting Software Data | Sage MAS 90 | Sage |
| .SOB | Apache Software Foundation | Data Files | OpenOffice.org Impress Bimap Styles File | Apache OpenOffice | Apache Software Foundation |
| .SOD | id Software | Data Files | Spear Of Destiny Data File | Spear of Destiny | id Software |
| .SOF | Apache Software Foundation | Data Files | Colour Palettes And Various Style Elements File | Apache OpenOffice | Apache Software Foundation |
| .SOFTWARE | Apple | Data Files | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .SOG | Apache Software Foundation | Data Files | Apache OpenOffice (OpenOffice.org) Colour Palettes | Apache OpenOffice | Apache Software Foundation |
| .SOM | Corel | Data Files | Corel Paradox Sort Information | Corel Paradox | Corel |
| .SONIC | Sonic Solutions | Data Files | DigitalMedia Project File | Roxio Creator NXT Pro 5 | Roxio |
| .SOR | Adobe Systems Incorporated | Data Files | Adobe Flash Media Server File System Object | Adobe Media Server | Adobe Systems Incorporated |
| .SOS | 3AM Solutions | Data Files | Dynamite VSP Swept Object Style File | Dynamite VSP | 3AM Solutions |
| .SOUND | Unknown Developer | Data Files | Unknown Apple II File. (found On Golden Orchard Apple II CD Rom) | Atom | GitHub, Inc. |
| .SOUP | Unknown Developer | Data Files | Message / E-mail File | Unknown Software | Unknown Developer |
| .SOURCE | Unknown Developer | Data Files | Unknown Apple II File. (found On Golden Orchard Apple II CD Rom) | Atom | GitHub, Inc. |
| .SP | Buchanan Computing | Data Files | SignPlot Traffic Sign File | SignPlot | Buchanan Computing |
| .SP1 | Microsoft Corporation | Data Files | Microsoft Windows XP With Service Pack 1 Installation Data | Microsoft Windows | Microsoft Corporation |
| .SP2 | Amusement Vision (SEGA) | Data Files | Super Ball 2 Level File | Super Ball 2 | Unknown Developer |
| .SP4 | Solutions Etcetera | Data Files | SuperCard 4 Player Project | Solutions Etcetera SuperCard | Solutions Etcetera |
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