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| Extension | File Type Developer | File Category | File Type Description | Primary Software | Primary Software Developer |
|---|---|---|---|---|---|
| .SAB | Spatial Corp | CAD Files | ACIS SAB Model File | TurboCAD Pro Platinum | IMSI/Design, LLC |
| .SAT | Spatial Corp | CAD Files | ACIS SAT 3D Model File | Autodesk Fusion 360 | Autodesk, Inc. |
| .SBP | Autodesk, Inc. | CAD Files | Sketchbook Express iCloud Image | SketchBook | Autodesk, Inc. |
| .SCH | Autodesk, Inc. | CAD Files | EAGLE Schematics File | Autodesk EAGLE | Autodesk, Inc. |
| .SDG | Golden Software LLC | CAD Files | Strater Project File | Strater | Golden Software LLC |
| .SDK | Autodesk, Inc. | CAD Files | AutoSketch Drawing | AutoSketch | Autodesk, Inc. |
| .SEW | S & S Computing | CAD Files | Home Embroidery Format | StudioPlus | Designer's Gallery software |
| .SGO | Volkswagen | CAD Files | ECU Update | Engine Control Unit (ECU) | Volkswagen |
| .SHE | CAD Schroer | CAD Files | Medusa 2D CAD File | Medusa | CAD Schroer |
| .SHX | Autodesk, Inc. | CAD Files | AutoCAD Compiled Shape File | Autodesk AutoCAD Civil 3D | Autodesk, Inc. |
| .SKCHR | Open Source | CAD Files | SketchChair Design | SketchChair | Open Source |
| .SKF | Autodesk, Inc. | CAD Files | AutoSketch Drawing | AutoSketch | Autodesk, Inc. |
| .SLC | Open Source | CAD Files | SLiCe Format Data | 3D Lightyear | 3D Systems |
| .SLDASM | Dassault Systèmes | CAD Files | SolidWorks Assembly File | Autodesk Fusion 360 | Autodesk, Inc. |
| .SLDDRW | Dassault Systèmes | CAD Files | SolidWorks Drawing File | Dassault Systemes SolidWorks | Dassault Systèmes |
| .SLDPRT | Dassault Systèmes | CAD Files | SolidWorks CAD Part File | Autodesk Fusion 360 | Autodesk, Inc. |
| .SM3 | DataCAD LLC | CAD Files | DataCAD Symbol File | DataCAD | DataCAD LLC |
| .SOS | 3AM Solutions | CAD Files | Dynamite VSP Swept Object Style File | Dynamite VSP | 3AM Solutions |
| .SPT | Interactive Data Visualization, Inc. | CAD Files | SpeedTree Tree Data File | SpeedTree Architect | Interactive Data Visualization, Inc. |
| .STD | Oracle Corporation | CAD Files | Apache OpenOffice Drawing Template | Apache OpenOffice | Apache Software Foundation |
| .STL | 3D Systems | CAD Files | Stereolithography File | Creo Parametric 3D Modeling Software | PTC |
| .STYXML | Autodesk, Inc. | CAD Files | Inventor Style Library File | Autodesk Inventor | Autodesk, Inc. |
| .SVD | Polytec | CAD Files | Scanning Vibrometer Data File | Polytec PSV Software | Polytec |
| .SXE | ProfiCAD | CAD Files | ProfiCAD Document | ProfiCAD | ProfiCAD |
| .SYM | The Eclipse Foundation | CAD Files | Symbols File | Eclipse CDT | The Eclipse Foundation |
| .SZN | ISD Group | CAD Files | HiCAD 3D CAD Drawing | HiCAD neXt | ISD Group |
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