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| Extension | File Type Developer | File Category | File Type Description | Software | Software Developer |
|---|---|---|---|---|---|
| .MAE | Interscape | Game Files | My Avatar Editor Character File | My Avatar Editor | Interscape |
| .MAX | Autodesk, Inc. | 3D Image Files | 3ds Max Scene File | PS2 Save Builder | Interscape |
| .MCH | Interscape | Settings Files | Machinery HDR Effects | Machinery HDR | Interscape |
| .MCP | Freescale | Developer Files | CodeWarrior Project | MegaCubo | Interscape |
| .MD | Various Developers | Developer Files | Markdown Documentation File | PS2 Save Builder | Interscape |
| .MDX | Disc Soft Ltd. | Disk Image Files | Extended Media Descriptor File | MDX Squisher | Interscape |
| .MFA | Clickteam | Developer Files | Multimedia Fusion Development File | Multimedia Fusion | Interscape |
| .MFW | MamiyaLeaf | Camera Raw Files | Mamiya Camera Raw File | Multimedia Fusion | Interscape |
| .MGN | Interscape | Database Files | Modern Genealogy Database File | Modern Genealogy | Interscape |
| .MHP | Open Source | Data Files | Maths Helper Plus File | MailShift | Interscape |
| .MHT | Various Developers | Web Files | MHTML Web Archive | WizBrother WizHtmlEditor | Interscape |
| .MHTM | Microsoft Corporation | Web Files | Mime HTML (MHTML) File | WizBrother WizHtmlEditor | Interscape |
| .MHTML | Microsoft Corporation | Web Files | Mime HTML (MHTML) File | WizBrother WizHtmlEditor | Interscape |
| .MII | Nintendo | Game Files | Wii Virtual Avatar File | My Avatar Editor | Interscape |
| .MIX | Microsoft Corporation | Raster Image Files | Microsoft Image Exchange File | Command and Conquer | Interscape |
| .MK3D | Matroska | Video Files | Matroska 3D Video File | MKVtoolnix | Interscape |
| .MKF | Interscape | Audio Files | KaraBox Karaoke Music File | KaraBox | Interscape |
| .MKZ | Interscape | Backup Files | PokerOffice Database Backup File | PokerOffice | Interscape |
| .MLA | Unknown Developer | Data Files | WorshipCenter Pro Document | WorshipCenter Pro | Interscape |
| .MLS | KIDASA Software, Inc. | Data Files | Milestones Simplicity File | WorshipCenter Pro | Interscape |
| .MMG | Moritz Bunkus | Settings Files | MKVToolNix Muxing Settings | MKVtoolnix | Interscape |
| .MMX | Interscape | Game Files | Command And Conquer Game Data | Command and Conquer | Interscape |
| .MOOV | Apple | Video Files | Apple QuickTime Movie | J2 Interactive MX Player | Interscape |
| .MOV | Apple | Video Files | Apple QuickTime Movie | J2 Interactive MX Player | Interscape |
| .MPL | Sony | Video Files | AVCHD Playlist File | J2 Interactive MX Player | Interscape |
| .MPO | CyberLink | Raster Image Files | CIPA Multi Picture Object File | S3D Viewer | Interscape |
| .MRD | Interscape | Text Files | MathRevolt Infinity Document | Infinity | Interscape |
| .MRP | Interscape | Data Files | Infinity Solution Plot Data | Infinity | Interscape |
| .MUL | OriginLab | Game Files | Ultima Online Multi File | MULTool | Interscape |
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