| .DLY | Xilinx, Inc. | Datové soubory | Xilinx ISE ReportGen Delay Information | ISE Design Suite | Xilinx, Inc. |
| .DLZ | CPT | Datové soubory | Crossword Power Tools Crossword Library File | Crossword Power Tools | CPT |
| .DM2 | Interscape | Datové soubory | Toad Data Modeler 2 File | Toad Data Modeler | Interscape |
| .DMC | nModal Solutions Inc. | Datové soubory | Datamartist Data Canvas File | nModal Solutions Datamartist | nModal Solutions Inc. |
| .DMD | Oracle Corporation | Datové soubory | SQL Developer Data Modeler File | SQL Developer Data Model | Oracle Corporation |
| .DME | Interscape | Datové soubory | Medical Manager DML System Merged Data | Medical Manager DML System | Emdeon Business Services, LLC |
| .DMG | Apple | Datové soubory | Mac OS X Disk Image File | 7-Zip | Igor Pavlov |
| .DMI | BYOND | Datové soubory | BYOND Dream Maker Icon File | BYOND | BYOND |
| .DML | Sybase, Inc | Datové soubory | DynaScript File | Internet Explorer | Microsoft Corporation |
| .DMM | Seavus | Datové soubory | iMindQ Mind Map File | Seavus iMindQ | Seavus |
| .DMO | Wouter van Oortmerssen | Datové soubory | Cube 2: Sauerbraten Demo File | Cube 2 Sauerbraten | Open Source |
| .DMP | Microsoft Corporation | Datové soubory | Windows Memory Dump File | Microsoft Visual Studio | Microsoft Corporation |
| .DMR | Brain Innovation | Datové soubory | BrainVoyager Diffusion Weighted Project File | BrainVoyager QX | Brain Innovation |
| .DMW | ScienceScope | Datové soubory | Datamass Ag File | Datamass Ag | ScienceScope |
| .DMY | PhysioNet | Datové soubory | SEMIA LTST DB Time Series Data File | SEMIA | PhysioNet |
| .DNA | GSL Biotech LLC | Datové soubory | SnapGene DNA File | SnapGene | GSL Biotech LLC |
| .DNC | Microsoft Corporation | Datové soubory | Windows Dancer File | Windows Media Center | Microsoft Corporation |
| .DND | European Bioinformatics Institute | Datové soubory | ClustalW2 Tree Data | ClustalW2 | European Bioinformatics Institute |
| .DNG | Adobe Systems Incorporated | Datové soubory | Digital Negative Image File | MacPhun ColorStrokes | Macphun |
| .DNT | Rockwell Automation Inc. | Datové soubory | RSNetWorx Project | RSNetWorx | Rockwell Automation Inc. |
| .DOCKZIP | Stardock Corporation | Datové soubory | ObjectDock File | Stardock ObjectDock | Stardock Corporation |
| .DOD | Progress Software Corporation | Datové soubory | Progress Artix Data Services Data Model | Progress Artix Data Services | Progress Software Corporation |
| .DOE | Rockwell Automation Inc. | Datové soubory | Rockwell Arena Model File | Rockwell Arena Simulation | Rockwell Automation Inc. |
| .DOI | Actuate Corporation | Datové soubory | BiRT Data Object Instance File | BIRT | Open Source |
| .DON | Apache Software Foundation | Datové soubory | Apache OpenOffice (OpenOffice.org) Log | Apache OpenOffice | Apache Software Foundation |
| .DOP | DxO Labs | Datové soubory | DxO Optics Pro Correction Settings File | DxO OpticsPro | DxO Labs |
| .DOT | Microsoft Corporation | Datové soubory | Word Document Template | Apache OpenOffice | Apache Software Foundation |
| .DOV | Safer Networking Ltd. | Datové soubory | Temporary (Temp) File | FileAlyzer | Safer Networking Ltd. |
| .DOWN | Apple | Datové soubory | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .DOX | Microsoft Corporation | Datové soubory | Visual Basic Binary UserDocument | Microsoft Visual Studio | Microsoft Corporation |
| .DP | Stefan Hagel | Datové soubory | Text Document | Microsoft Notepad | Microsoft Corporation |
| .DP4 | Apian Software | Datové soubory | DecisionPad 4 Project | DecisionPad | Apian Software |
| .DPB | Susteen, Inc. | Datové soubory | DataPilot Backup File | DataPilot | Susteen, Inc. |
| .DPC | Microsoft Corporation | Datové soubory | Microsoft Office Resource File | Microsoft Office | Microsoft Corporation |
| .DPD | David Pilling | Datové soubory | Ovation Pro File | Ovation Pro Reader | David Pilling |
| .DPE | Procedimientos-Uno, S.L. | Datové soubory | DPwinEHE Project File | DPwinEHE | Interscape |
| .DPF | Open Source | Datové soubory | Dargon Package | Dargon | Open Source |
| .DPJ | Delft Spline Systems | Datové soubory | DeskProto Project | DeskProto | Delft Spline Systems |
| .DPN | Depiction Inc. | Datové soubory | Depiction Data File | Depiction | Depiction Inc. |
| .DPO | DECAdry | Datové soubory | DECAdry Express Business Cards Business Card | DECAdry Express Business Cards | DECAdry |
| .DPS | DivX, LLC. | Datové soubory | DivX Player 2 Skin File | DivX | DivX, LLC. |
| .DPT | Kingsoft | Datové soubory | Kingsoft Presentation Template | Kingsoft Office | Kingsoft |
| .DPX | Kodak | Datové soubory | Digital Picture Exchange File | Adobe SpeedGrade | Adobe Systems Incorporated |
| .DQC | Open Source | Datové soubory | CP/M Disk Information Data | CP/M | Open Source |
| .DR | Sony Mobile Communications | Datové soubory | DRM Rights Object | DRM Packager | Sony Mobile Communications |
| .DRAFT | Apple | Datové soubory | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .DRB | Dr. Software | Datové soubory | Dr. Beam Pro Data | Dr. Beam Pro | Dr. Software |
| .DRC | Open Source | Datové soubory | Open Mobile Alliance DRM Rights Object | Microsoft Notepad | Microsoft Corporation |
| .DRE | DÖRR EDV-Beratung | Datové soubory | DReport Exported Report | DReport | DÖRR EDV-Beratung |
| .DRIVE | Apple | Datové soubory | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .DRIVERS | Apple | Datové soubory | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .DRL | Gerber Technology | Datové soubory | Gerber Drill Rack File | Altium Designer | Altium |
| .DRN | Unknown Developer | Datové soubory | Darn for DOS Data File | Darn software | Unknown Developer |
| .DRO | Open Source | Datové soubory | DOSBox Raw OPL Format | DOSBox | Open Source |
| .DRT | Micrografx | Datové soubory | Micrografix Windows Draw Template File | Micrografix Windows Draw | Micrografx |
| .DRX | Adobe Systems Incorporated | Datové soubory | Adobe Photoshop Tutorial Data | Adobe Photoshop | Adobe Systems Incorporated |
| .DRY | Unknown Developer | Datové soubory | XAIRON Organizer Diary File | XAIRON Organizer | Unknown Developer |
| .DRZ | Unknown Developer | Datové soubory | Draz Paint File | XnView MP | XnSoft |
| .DS | DAZ 3D | Datové soubory | DAZ Studio 1/2 Script | DAZ Studio | DAZ 3D |
| .DSB | Dell Technologies | Datové soubory | Dell DataSafe Backup File | DataSafe Local Backup | Dell Technologies |
| .DSC | Kingsoft | Datové soubory | Kingsoft Design Science Equation File | Kingsoft Office | Kingsoft |
| .DSD | Autodesk, Inc. | Datové soubory | AutoCAD Drawing Set Description File | Autodesk AutoCAD | Autodesk, Inc. |
| .DSE | DAZ 3D | Datové soubory | DAZ Studio Encrypted Script | DAZ Studio | DAZ 3D |
| .DSHADER | Microsoft Corporation | Datové soubory | Microsoft Visual Studio Text Data | Microsoft Visual Studio | Microsoft Corporation |
| .DSL | ABBYY | Datové soubory | Lingvo Dictionary Data File | ABBYY Lingvo Dictionary | ABBYY |
| .DSR | Activision | Datové soubory | Modern Warfare 3 Dedicated Server Recipe File | Call of Duty 4: Modern Warfare | Activision |
| .DSSLIDESHOW | Idea2 s.c. | Datové soubory | Desktop Sidebar Slideshow Panel File | Desktop Sidebar | Idea2 s.c. |
| .DSX | DAZ 3D | Datové soubory | DAZ Studio XML File | DAZ Studio | DAZ 3D |
| .DSY | Lead System (M) Sdn. Bhd. | Datové soubory | Besta Video File | Besta Electronic Dictionaries | Lead System (M) Sdn. Bhd. |
| .DSZ | Orchida Soft | Datové soubory | Orchida (OES) Embroidery File | Orchida Embroidery System | Orchida Soft |
| .DT | d-lusion interactive media | Datové soubory | Drum Station Machine State File | Drum Station | d-lusion interactive media |
| .DT? | Terry A. Davis | Datové soubory | LoseThos Data File | LoseThos | Terry A. Davis |
| .DTA | IWIS | Datové soubory | Chain Engineering Database | Chain Engineering | IWIS |
| .DTC | Microsoft Corporation | Datové soubory | Windows Application Log File | Microsoft Windows Millenium Edition | Microsoft Corporation |
| .DTD | Syncro Soft | Datové soubory | Document Type Definition File | Microsoft Notepad | Microsoft Corporation |
| .DTE | DoroTree Technologies | Datové soubory | DoroTree Family Tree Data | DoroTree | DoroTree Technologies |
| .DTERMLICENCE | Decimus Software, Inc. | Datové soubory | DTerm Licence File | DTerm | Decimus Software, Inc. |
| .DTH | Microsoft Corporation | Datové soubory | Microsoft Windows Application Log File | Microsoft Windows | Microsoft Corporation |
| .DTI | Microsoft Corporation | Datové soubory | Microsoft Windows Application Log File | Microsoft Windows | Microsoft Corporation |
| .DTM | Prodatron | Datové soubory | DigiTrakker Audio Module | CocoModX | Open Source |
| .DTR | Swisslog | Datové soubory | Swisslog Downtime Analyzer Report | Unknown Software | Unknown Developer |
| .DUMP | Microsoft Corporation | Datové soubory | Dump File | macOS | Apple |
| .DUT | Microsoft Corporation | Datové soubory | Dutch Localization Language | Microsoft Notepad | Microsoft Corporation |
| .DVC | IBM | Datové soubory | Lotus 1-2-3 Data | Lotus 1-2-3 | IBM |
| .DVDFABHDDECRYPTER | Fengtao Software Inc. | Datové soubory | DVDFab HD Decrypter File | DVDFab HD Decrypter | Fengtao Software Inc. |
| .DVDFABPLATINUM5 | Fengtao Software Inc. | Datové soubory | DVDFab Platinum File | DVDFab | Fengtao Software Inc. |
| .DVDPROJ | Apple | Datové soubory | iDVD Project File | Apple iDVD | Apple |
| .DVO | DVO Enterprises | Datové soubory | Cook'n Cookbook File | DVO Enterprises Cook'n | DVO Enterprises |
| .DW4 | IBM | Datové soubory | Visio/DisplayWrite 4 Text File | DisplayWrite | IBM |
| .DWB | Coryphaeus Software | Datové soubory | Designer's Workbench File Format | Designer's Workbench | Coryphaeus Software |
| .DWI | KONAMI | Datové soubory | Dance With Intensity Song File | ArrowVortex | Bram van de Wetering |
| .DWM | Open Source | Datové soubory | Digital Works Circuit Project | Digital Works | Open Source |
| .DWS | Autodesk, Inc. | Datové soubory | AutoCAD Drawing Standards File | Autodesk AutoCAD | Autodesk, Inc. |
| .DWX | Capilano Computing | Datové soubory | DesignWorks Viewer Tools Data | DesignWorks | Capilano Computing |
| .DWZ | Corel | Datové soubory | DVD MovieFactory Project File | DVD MovieFactory | Corel |
| .DX | Digital Equipment Corporation | Datové soubory | DEC WPS Plus File | Microsoft Notepad | Microsoft Corporation |
| .DXL | IBM | Datové soubory | Domino XML Language File | Microsoft Notepad | Microsoft Corporation |
| .DXV | Condrey Corporation | Datové soubory | DocXchanger Data | DocXchanger | Condrey Corporation |
| .DYNAMO | Apple | Datové soubory | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .DZC | Microsoft Corporation | Datové soubory | Photosynth Deep Zoom Collection | Microsoft PhotoSynth | Microsoft Corporation |
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