| .DAE | Sony | Soubory 3D obrázků | Digital Asset Exchange File | Adobe Photoshop CC | Adobe Systems Incorporated |
| .DATA | Appricon | Datové soubory | Analysis Studio Offline Data | Adobe Soundbooth | Adobe Systems Incorporated |
| .DBF | dBase, LLC | Databázové soubory | Database File | JetForm FormFlow | Adobe Systems Incorporated |
| .DBM | Adobe Systems Incorporated | Webové soubory | ColdFusion Server File | Adobe ColdFusion Builder | Adobe Systems Incorporated |
| .DC2 | Kodak | Rastrové obrazové soubory | Kodak Digital Camera RAW Image File | Adobe Photoshop | Adobe Systems Incorporated |
| .DCM | National Electrical Manufacturers Association (NEMA) | Rastrové obrazové soubory | DICOM Image File Format | Adobe Photoshop | Adobe Systems Incorporated |
| .DCP | Embarcadero Technologies | Soubory pro vývojáře | Delphi Compiled Package | Adobe Photoshop CC | Adobe Systems Incorporated |
| .DCS | Quark Software Inc. | Vektorové obrazové soubory | Desktop Color Separation File | Adobe Illustrator CC | Adobe Systems Incorporated |
| .DCX | ZSoft Corporation | Rastrové obrazové soubory | Zsoft Multi-Page Paintbrush File | Adobe Photoshop | Adobe Systems Incorporated |
| .DDS | Microsoft Corporation | Rastrové obrazové soubory | DirectDraw Surface | Adobe Photoshop | Adobe Systems Incorporated |
| .DEU | Adobe Systems Incorporated | Datové soubory | Adobe Reader German Language File | Adobe Reader | Adobe Systems Incorporated |
| .DFM | Open Source | Textové soubory | Pascal File | ExtendScript Toolkit (ESTK) | Adobe Systems Incorporated |
| .DHY | Adobe Systems Incorporated | Datové soubory | Adobe Bridge Information File | Adobe Bridge CC | Adobe Systems Incorporated |
| .DIB | The GIMP Development Team | Rastrové obrazové soubory | Device Independent Bitmap File | Adobe Illustrator CC | Adobe Systems Incorporated |
| .DIM | Active@ Data Recovery Software | Soubory záloh | Active@ Raw Disk Image Backup File | Adobe Dimensions | Adobe Systems Incorporated |
| .DIR | Adobe Systems Incorporated | Video soubory | Adobe Director Movie | Adobe Director | Adobe Systems Incorporated |
| .DLG | Crytek | Soubory her | Crysis Dialogue Data File | ExtendScript Toolkit (ESTK) | Adobe Systems Incorporated |
| .DLM | AKAMAI | Neobvyklé soubory | Akamai Download Manager File | Adobe Creative Cloud | Adobe Systems Incorporated |
| .DLV | Dassault Systèmes | Soubory CAD | CATIA 4 Export File | Adobe Acrobat DC | Adobe Systems Incorporated |
| .DLX | DIAL | Soubory CAD | DIALux Document | Adobe Premiere Pro CC | Adobe Systems Incorporated |
| .DMV | Adobe Systems Incorporated | Soubory nastavení | Adobe Acrobat Catalog Data | Adobe Acrobat DC | Adobe Systems Incorporated |
| .DNG | Adobe Systems Incorporated | Soubory Camera Raw | Digital Negative Image File | Adobe Photoshop Elements | Adobe Systems Incorporated |
| .DOG | Ubisoft Blue Byte | Soubory her | Dogz Dog Description File | Adobe Photoshop Elements | Adobe Systems Incorporated |
| .DPX | Kodak | Rastrové obrazové soubory | Digital Picture Exchange File | Adobe SpeedGrade | Adobe Systems Incorporated |
| .DRT | Micrografx | Grafické soubory | Micrografix Windows Draw Template File | Adobe Director | Adobe Systems Incorporated |
| .DRX | Adobe Systems Incorporated | Datové soubory | Adobe Photoshop Tutorial Data | Adobe Photoshop | Adobe Systems Incorporated |
| .DV | Roxio | Video soubory | Digital Video File | Adobe Flash Professional CC | Adobe Systems Incorporated |
| .DWG | Autodesk, Inc. | Soubory CAD | AutoCAD Drawing Database File | Adobe Illustrator CC | Adobe Systems Incorporated |
| .DWS | Autodesk, Inc. | Soubory CAD | AutoCAD Drawing Standards File | Adobe Dreamweaver | Adobe Systems Incorporated |
| .DWT | Adobe Systems Incorporated | Webové soubory | Dreamweaver Web Page Template | Adobe Dreamweaver | Adobe Systems Incorporated |
| .DXF | Autodesk, Inc. | Soubory CAD | Drawing Exchange Format | Adobe Illustrator CC | Adobe Systems Incorporated |
| .DXR | Adobe Systems Incorporated | Video soubory | Protected Macromedia Director Movie | Adobe Director | Adobe Systems Incorporated |
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